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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Foxn1
forkhead box N1
MGI:102949
49 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Btnl1tm1(KOMP)Mbp/Btnl1tm1(KOMP)Mbp
Foxn1nu/Foxn1nu
involves: albino stock * C57BL/6N 		decreased gamma-delta intraepithelial T cell number J:236526
Dh/Dh+
Foxn1nu/Foxn1nu
involves: N:NIH(S) 		abnormal Peyer's patch morphology J:6062
absent spleen J:6062
athymia J:6062
decreased leukocyte cell number J:6062
increased erythroid progenitor cell number J:6062
increased IgA level J:6062
thrombocytosis J:6062
Dicer1tm1Tara/Dicer1tm1Tara
Foxn1tm3(cre)Nrm/Foxn1+
involves: 129P2/OlaHsd * C57BL/6NHsd 		abnormal positive T cell selection J:180783
abnormal thymus cortex morphology J:180783
abnormal thymus epithelium morphology J:180783
abnormal thymus involution J:180783
abnormal thymus medulla morphology J:180783
abnormal thymus morphology J:180783
abnormal thymus physiology J:180783
decreased CD4-positive, alpha-beta T cell number J:180783
decreased CD8-positive, alpha-beta T cell number J:180783
increased susceptibility to induced arthritis J:180783
Dll4tm1Frad/Dll4tm1Frad
Foxn1tm3(cre)Nrm/Foxn1+
B6.Cg-Dll4tm1Frad Foxn1tm3(cre)Nrm 		abnormal T cell differentiation J:143472
abnormal thymus cell ratio J:143472
decreased CD4-positive, alpha-beta T cell number J:143472
decreased CD8-positive, alpha-beta T cell number J:143472
decreased double-positive T cell number J:143472
decreased thymocyte number J:143472
increased immature B cell number J:143472
Dmdmdx/Y
Foxn1nu/Foxn1nu
involves: C57BL/10ScSn 		abnormal muscle morphology J:95776
decreased skeletal muscle fiber size J:95776
increased skeletal muscle fiber size J:95776
Foxn1nu/Foxn1nu
Fv4r/Fv4r
involves: BALB/c 		decreased susceptibility to Retroviridae infection J:5684, J:5714
Foxn1nu/Foxn1nu
Gpc1tm1.1Alan/Gpc1tm1.1Alan
involves: CD-1 		abnormal response/metabolism to endogenous compounds J:130809
decreased metastatic potential J:130809
Foxn1nu/Foxn1nu
Ivltm1Dji/Ivltm1Dji
involves: 129S4/SvJae * BALB/c * C57BL/6 		no abnormal phenotype detected J:65192
Foxn1nu/Foxn1nu
Map3k14aly/Map3k14aly
involves: BALB/cAJcl * C57BL/6J 		absent B cells J:96579
absent lymph nodes J:96579
absent Peyer's patches J:96579
athymia J:96579
decreased gamma-delta intraepithelial T cell number J:96579
decreased T cell number J:96579
Foxn1nu/Foxn1nu
Msx2tm1Rilm/Msx2tm1Rilm
involves: 129S4/SvJae * BALB/c * CD-1 		abnormal nail bed morphology J:173664
abnormal nail matrix morphology J:173664
abnormal nail morphology J:173664
abnormal nail plate morphology J:173664
deformed nails J:173664
short nails J:173664
Foxn1nu/Foxn1nu
Srcr/Srcr+
involves: BALB/c * C57BL/6 		decreased tumor incidence J:83618
Foxn1nu/Foxn1nu
Tgfb1tm1Doe/Tgfb1tm1Doe
involves: 129S2/SvPas * BALB/c * CF-1 		abnormal T cell physiology J:99033
decreased inflammatory response J:99033
premature death J:99033
Foxn1tm3(cre)Nrm/Foxn1+
Gt(ROSA)26Sortm1(Tbx1)Rche/Gt(ROSA)26Sor+
involves: C57BL/6 * C57BL/6NHsd 		abnormal third pharyngeal pouch morphology J:214094
abnormal thymus development J:214094
abnormal thymus epithelium morphology J:214094
decreased thymocyte number J:214094
thymus hypoplasia J:214094
Foxn1tm3(cre)Nrm/Foxn1+
Mir205hgtm1Oers/Mir205hgtm1Oers
B6(Cg)-Mir205hgtm1Oers Foxn1tm3(cre)Nrm 		decreased thymocyte number J:278363
decreased thymus weight J:278363
thymus hypoplasia J:278363
Foxp3tm1Ayr/Foxp3tm1Ayr
Foxn1tm3(cre)Nrm/Foxn1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		normal immune system phenotype J:125405
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory