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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ptgdr
prostaglandin D receptor
MGI:102966
18 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ptgdrtm1Dgen/Ptgdr+
B6.129P2-Ptgdrtm1Dgen 		decreased vasodilation J:109107
increased vasodilation J:109107
Ptgdrtm1Dgen/Ptgdrtm1Dgen
B6.129P2-Ptgdrtm1Dgen 		decreased vasodilation J:109107
Ptgdrtm1Sna/Ptgdrtm1Sna
B6.129P2-Ptgdrtm1Sna/Sna 		abnormal dermal mast cell morphology J:197334
abnormal mast cell physiology J:197334
abnormal vascular permeability J:197334
decreased mast cell degranulation J:197334
decreased mast cell histamine storage J:197334
decreased susceptibility to type I hypersensitivity reaction J:197334
Ptgdrtm1Sna/Ptgdrtm1Sna
involves: 129P2/OlaHsd * C57BL/6 		abnormal macrophage activation involved in immune response J:243958
brain inflammation J:243958
decreased microglial cell activation J:243958
increased CD4-positive, alpha-beta T cell number J:243958
increased interleukin-1 beta secretion J:243958
increased regulatory T cell number J:243958
increased susceptibility to Coronaviridae infection J:243958
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:243958
respiratory system inflammation J:61023
spongiform encephalopathy J:243958
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory