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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Klra8
killer cell lectin-like receptor, subfamily A, member 8
MGI:102968
13 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Klra8Cmv1-del/Klra8Cmv1-r
(BXD8/TyJ x C57BL/6)F1 		decreased susceptibility to Herpesvirales infection J:79093
Klra8Cmv1-del/Klra8Cmv1-s
(BXD8/TyJ x BALB/c)F1 		increased susceptibility to Herpesvirales infection J:79093
Klra8Cmv1-del/Klra8Cmv1-s
(BXD8/TyJ x DBA/2)F1 		increased susceptibility to Herpesvirales infection J:79093
Klra8Cmv1-r/Klra8Cmv1-r
C.B6-Klra8Cmv1-r 		decreased IgG1 level J:97203
decreased IgG2a level J:97203
decreased IgG2b level J:97203
decreased IgG3 level J:97203
decreased IgG level J:97203
decreased interleukin-4 secretion J:97203
decreased susceptibility to Herpesvirales infection J:22486, J:79093
decreased transforming growth factor beta level J:97203
increased circulating interferon-gamma level J:97203
increased IgM level J:97203
increased susceptibility to infection induced morbidity/mortality J:97203
increased susceptibility to parasitic infection J:97203
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory