About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Stat6
signal transducer and activator of transcription 6
MGI:103034
42 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Cd28tm1Mak/Cd28tm1Mak
Stat6tm1Gru/Stat6tm1Gru
C.129S2(B6)-Cd28tm1Mak Stat6tm1Gru 		increased susceptibility to parasitic infection J:90987
Fbn1Tsk/Fbn1+
Stat6tm1Gru/Stat6tm1Gru
involves: 129S2/SvPas * C57BL/10 * DBA/2 		decreased interleukin-4 secretion J:57957
emphysema J:57957
normal integument phenotype J:57957
Foxp3tm1Tch/Y
Stat6tm1Gru/Stat6tm1Gru
C.129-Stat6tm1Gru Foxp3tm1Tch 		abnormal cytokine secretion J:117165
normal immune system phenotype J:117165
increased circulating interferon-gamma level J:117165
increased eosinophil cell number J:117165
lethality at weaning, complete penetrance J:117165
normal respiratory system phenotype J:117165
Il4tm1.1Wep/Il4+
Stat6tm1Gru/Stat6tm1Gru
C.129-Stat6tm1Gru Il4tm1.1Wep 		abnormal T-helper 2 cell differentiation J:138827
decreased IgE level J:138827
impaired eosinophil recruitment J:138827
Il4tm1.1Wep/Il4tm1.1Wep
Stat6tm1Gru/Stat6tm1Gru
C.129-Stat6tm1Gru Il4tm1.1Wep 		abnormal T-helper 2 cell differentiation J:138827
decreased IgE level J:138827
impaired eosinophil recruitment J:138827
Nfkbiztm1Aki/Nfkbiz+
Stat6tm1Aki/Stat6tm1Aki
C.129P2-Stat6tm1Aki Nfkbiztm1Aki 		acanthosis J:141704
skin inflammation J:141704
Nfkbiztm1Aki/Nfkbiztm1Aki
Stat6tm1Aki/Stat6tm1Aki
C.129P2-Stat6tm1Aki Nfkbiztm1Aki 		abnormal conjunctival epithelium morphology J:141704
blepharitis J:141704
dermatitis J:141704
epidermal hyperplasia J:141704
eye inflammation J:141704
hyperkeratosis J:141704
skin edema J:141704
skin inflammation J:141704
Socs1tm1Kish/Socs1tm1Kish
Stat6tm1Aki/Stat6tm1Aki
involves: 129P2/OlaHsd * C57BL/6 		decreased body size J:69472
enlarged liver J:69472
normal immune system phenotype J:69472
increased activated T cell number J:69472
liver inflammation J:69472
postnatal growth retardation J:69472
premature death J:69472
thymus atrophy J:69472
Stat4tm1Jni/Stat4tm1Jni
Stat6tm1Jni/Stat6tm1Jni
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 		decreased interleukin-4 secretion J:96338
increased interferon-gamma secretion J:96338
increased susceptibility to autoimmune diabetes J:96338
Stat6tm1Aki/Stat6tm1Aki
Tg(KRT14-CASP1)1Miz/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal circulating histamine level J:78602
decreased IgE level J:78602
decreased IgG1 level J:78602
dermatitis J:78602
excessive scratching J:78602
increased circulating interleukin-18 level J:78602
Stat6tm1Gru/Stat6+
Tg(Scgb1a1-Il13)2Eli/?
involves: 129S2/SvPas * C57BL/6 * CBA 		abnormal lung morphology J:132385
abnormal lung size J:132385
abnormal pulmonary alveolus morphology J:132385
abnormal respiratory system morphology J:132385
abnormal respiratory system physiology J:132385
overexpanded pulmonary alveolus J:132385
respiratory system inflammation J:132385
Stat6tm1Gru/Stat6tm1Gru
Tg(Scgb1a1-Il13)2Eli/?
involves: 129S2/SvPas * C57BL/6 * CBA 		normal respiratory system phenotype J:132385
Stat6tm1Gru/Stat6tm1Gru
Tg(Scgb1a1-Il13)2Eli/?
Tg(Scgb1a1-STAT6)1Erle/?
involves: 129S2/SvPas * C57BL/6 * CBA * FVB 		abnormal respiratory system physiology J:132385
normal respiratory system phenotype J:132385
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory