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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Stat2
signal transducer and activator of transcription 2
MGI:103039
10 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Stat2m1Btlr/Stat2m1Btlr
C57BL/6J-Stat2m1Btlr 		decreased CD8-positive, alpha-beta T cell number J:265265
decreased central memory CD8 positive, alpha-beta T cell number J:265265
decreased single-positive T cell number J:265265
Stat2p117/Stat2p117
C57BL/6J-Stat2P117 		abnormal level of surface class II molecules J:164049
decreased dendritic cell number J:164049
decreased level of surface class I molecules J:164049
decreased plasmacytoid dendritic cell number J:164049
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:164049
Stat2tm1Shnd/Stat2tm1Shnd
involves: 129S1/Sv * 129X1/SvJ 		abnormal T cell differentiation J:66564
increased susceptibility to Riboviria infection J:66564
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory