Stat4 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stat4
signal transducer and activator of transcription 4
MGI:103062

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Stat4^tm1Gru/Stat4^tm1Gru Tg(Ins2-GP)34-20Olds/0 involves: 129S2/SvPas * BALB/c * C57BL/6	abnormal susceptibility to autoimmune disorder	J:107047
Stat4^tm1Gru/Stat4^tm1Gru Tg(Ins2-NP)25-3Olds/0 involves: 129S2/SvPas * BALB/c * C57BL/6	abnormal cytotoxic T cell physiology	J:107047
	decreased interferon-gamma secretion	J:107047
	decreased susceptibility to autoimmune diabetes	J:107047
	insulitis	J:107047
Stat4^tm1Jni/Stat4^tm1Jni Stat6^tm1Jni/Stat6^tm1Jni involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6	decreased interleukin-4 secretion	J:96338
	increased interferon-gamma secretion	J:96338
	increased susceptibility to autoimmune diabetes	J:96338

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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