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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Stat1
signal transducer and activator of transcription 1
MGI:103063
30 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Col1a1tm1(tetO-Stat1)Biat/Col1a1tm1(tetO-Stat1)Biat
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
Stat1tm1Dlv/Stat1tm1Dlv
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 		abnormal susceptibility to infection induced morbidity/mortality J:212694
Il6sttm1Ern/Il6sttm1Ern
Stat1tm1Rds/Stat1tm1Rds
involves: 129S1/Sv 		abnormal inflammatory response J:139226
Ptpn6m1Btlr/Ptpn6m1Btlr
Stat1m1Btlr/Stat1m1Btlr
C57BL/6J-Stat1m1Btlr Ptpn6m1Btlr 		ulcerated autopod J:142845
Rag2tm1Fwa/Rag2tm1Fwa
Stat1tm1Rds/Stat1tm1Rds
involves: 129S/SvEv * 129S6/SvEvTac 		increased gastrointestinal tumor incidence J:216040
increased mammary adenocarcinoma incidence J:216040
Socs1tm1Kish/Socs1tm1Kish
Stat1tm1Rds/Stat1tm1Rds
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 		decreased body size J:69472
enlarged liver J:69472
normal immune system phenotype J:69472
increased activated T cell number J:69472
liver inflammation J:69472
postnatal growth retardation J:69472
premature death J:69472
thymus atrophy J:69472
Stat1tm1Dlv/Stat1tm1Dlv
Tg(ANPEP)270Mmul/Tg(ANPEP)270Mmul
involves: 129S/SvEv * ICR 		increased susceptibility to Coronaviridae infection J:99728
internal hemorrhage J:99728
Stat1tm1Dlv/Stat1tm1Dlv
Tg(ANPEP)861Mmul/Tg(ANPEP)861Mmul
involves: 129S/SvEv * ICR 		increased susceptibility to Coronaviridae infection J:99728
lung hemorrhage J:99728
small intestine hemorrhage J:99728
Stat1tm1Mam/Stat1tm1Mam
Tg(MMTV-Erbb2*,-cre)1Mul/0
involves: 129S/SvEv * FVB 		decreased tumor latency J:169262
Stat1tm1Rds/Stat1tm1Rds
Stat2tm1Shnd/Stat2tm1Shnd
involves: 129/Sv * 129S1/Sv * 129X1/SvJ 		increased susceptibility to Riboviria infection J:66564
Stat1tm1Rds/Stat1tm1Rds
Stat3tm2Aki/Stat3tm2Aki
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 		abnormal colon morphology J:83280
colitis J:83280
increased CD4-positive, alpha-beta T cell number J:83280
increased interferon-gamma secretion J:83280
increased interleukin-6 secretion J:83280
increased tumor necrosis factor secretion J:83280
Stat1tm1Rds/Stat1tm1Rds
Tg(GFAP-tTA)67Pop/0
Tg(tetO-Ifng)184Pop/0
involves: 129S/SvEv * C57BL/6 * DBA/2 		ataxia J:94092
normal mortality/aging J:94092
normal neoplasm J:94092
prenatal lethality, complete penetrance J:94092
tremors J:94092
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory