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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ddx3x
DEAD box helicase 3, X-linked
MGI:103064
33 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ddx3xtm1.1Lyou/Ddx3x+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129 * C57BL/6 * CBA 		no abnormal phenotype detected J:231798
Ddx3xtm1.1Lyou/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129 * C57BL/6 * CBA 		abnormal allantois morphology J:231798
abnormal brain development J:231798
abnormal cell cycle J:231798
abnormal cell physiology J:231798
abnormal developmental patterning J:231798
abnormal embryo turning J:231798
abnormal head fold morphology J:231798
abnormal myocardial trabeculae morphology J:231798
abnormal neural tube closure J:231798
embryonic growth retardation J:231798
embryonic lethality prior to tooth bud stage J:231798
failure of chorioallantoic fusion J:231798
increased embryonic tissue cell apoptosis J:231798
increased mitotic index J:231798
microcephaly J:231798
pericardial effusion J:231798
preweaning lethality, complete penetrance J:231798
small allantois J:231798
Ddx3xtm1.2Lyou/Y
involves: 129 * C57BL/6 		decreased trophoblast giant cell number J:231798
embryonic growth retardation J:231798
embryonic lethality between implantation and placentation, incomplete penetrance J:231798
embryonic lethality prior to organogenesis, complete penetrance J:231798
Ddx3xtm1.2Lyou/Ddx3x+
involves: 129 * C57BL/6 		abnormal placenta vasculature J:231798
abnormal placental labyrinth vasculature morphology J:231798
abnormal trophoblast giant cell morphology J:231798
decreased spongiotrophoblast cell number J:231798
decreased spongiotrophoblast size J:231798
decreased trophoblast giant cell number J:231798
edema J:231798
embryonic growth retardation J:231798
hemorrhage J:231798
lethality throughout fetal growth and development, incomplete penetrance J:231798
normal mortality/aging J:231798
preweaning lethality, complete penetrance J:231798
small placenta J:231798
ventricular septal defect J:231798
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory