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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atrx
ATRX, chromatin remodeler
MGI:103067
35 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
AtrxGt(E085A04)Wrst/Y
chimera involves: 129P2/OlaHsd 		abnormal developmental patterning J:160967
embryonic lethality during organogenesis, complete penetrance J:160967
AtrxGt(P034C09)Wrst/Y
chimera involves: 129S6/SvEvTac * C57BL/6 		abnormal developmental patterning J:160967
AtrxGt(P034D09)Wrst/Y
chimera involves: 129S6/SvEvTac * C57BL/6J 		abnormal developmental patterning J:160967
abnormal heart morphology J:160967
Atrxtm1Enl/Atrxtm1Enl
B6.129S4-Atrxtm1Enl 		normal behavior/neurological phenotype J:168608
decreased body weight J:168608
impaired contextual conditioning behavior J:168608
prenatal lethality, incomplete penetrance J:168608
reduced long-term potentiation J:168608
Atrxtm1Rjg/Atrx+
Tg(Gata1-cre)1Sho/0
involves: 129P2/OlaHsd * C57BL/6 * CD-1 		abnormal behavior J:115836
abnormal imprinting J:115836
abnormal reproductive system physiology J:115836
embryonic lethality during organogenesis, incomplete penetrance J:115836
Atrxtm1Rjg/Y
Foxg1tm1(cre)Skm/Foxg1+
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal suckling behavior J:95953
absent dentate gyrus J:95953
absent gastric milk in neonates J:95953
decreased birth body size J:95953
decreased hippocampus pyramidal cell number J:95953
loss of cortex neurons J:95953
loss of hippocampal neurons J:95953
postnatal lethality, complete penetrance J:95953
Atrxtm1Rjg/Y
Tg(Gata1-cre)1Sho/0
involves: 129P2/OlaHsd * C57BL/6 * CD-1 		abnormal ectoplacental cone morphology J:115836
abnormal trophectoderm morphology J:115836
decreased cell proliferation J:115836
decreased embryo size J:115836
decreased trophoblast giant cell number J:115836
disorganized extraembryonic tissue J:115836
embryonic growth retardation J:115836
embryonic lethality during organogenesis, complete penetrance J:115836
small ectoplacental cone J:115836
Atrxtm1Rjg/Y
Tg(Nes-cre)2472Pick/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		decreased birth body size J:95953
loss of cortex neurons J:95953
loss of hippocampal neurons J:95953
postnatal lethality, incomplete penetrance J:95953
Atrxtm1Rjg/Y
Tg(Pax6-cre,GFP)2Pgr/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal eye electrophysiology J:145002
abnormal retina ganglion layer morphology J:145002
abnormal retina horizontal cell morphology J:145002
abnormal retina inner nuclear layer morphology J:145002
abnormal retina morphology J:145002
decreased amacrine cell number J:145002
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory