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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pura
purine rich element binding protein A
MGI:103079
42 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Puratm1Herm/Pura+
involves: 129P2/OlaHsd * BALB/c 		abnormal neuron proliferation J:179606
increased brain weight J:179606
Puratm1Herm/Puratm1Herm
involves: 129P2/OlaHsd * BALB/c 		abnormal axon morphology J:179606
abnormal dentate gyrus morphology J:179606
abnormal gait J:179606
abnormal hippocampus stratum lacunosum morphology J:179606
abnormal neuron proliferation J:179606
decreased cerebellar granule cell number J:179606
decreased Purkinje cell number J:179606
increased brain size J:179606
increased brain weight J:179606
postnatal lethality, incomplete penetrance J:179606
premature death J:179606
tremors J:179606
weakness J:179606
weight loss J:179606
Puratm1Kkh/Pura+
involves: 129 		decreased cell proliferation J:85759
decreased DNA replication J:85759
postnatal growth retardation J:85759
seizures J:85759
Puratm1Kkh/Puratm1Kkh
involves: 129 		abnormal brain white matter morphology J:85759
abnormal bronchiole epithelium morphology J:85759
abnormal cerebellar cortex morphology J:85759
abnormal cerebellar granule layer morphology J:85759
abnormal cerebellar molecular layer J:85759
abnormal cerebellum development J:85759
abnormal cerebellum external granule cell layer morphology J:85759
abnormal cerebellum morphology J:85759
abnormal gait J:85759
abnormal hippocampus morphology J:85759
abnormal nervous system tract morphology J:85759
abnormal posture J:85759
abnormal spleen morphology J:85759
abnormal tail movements J:85759
abnormal thymus morphology J:85759
cerebellum hypoplasia J:85759
decreased cell proliferation J:85759
decreased CNS synapse formation J:85759
decreased DNA replication J:85759
decreased locomotor activity J:85759
decreased neuron number J:85759
decreased neuronal precursor proliferation J:85759
decreased Purkinje cell number J:85759
decreased Purkinje cell size J:85759
decreased spleen weight J:85759
premature death J:85759
reticulocytopenia J:85759
seizures J:85759
slow postnatal weight gain J:85759
small spleen J:85759
tremors J:85759
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory