Pura Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pura
purine rich element binding protein A
MGI:103079

42 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pura^tm1Herm/Pura⁺ involves: 129P2/OlaHsd * BALB/c	abnormal neuron proliferation	J:179606
Pura^tm1Herm/Pura⁺ involves: 129P2/OlaHsd * BALB/c	increased brain weight	J:179606
Pura^tm1Herm/Pura^tm1Herm involves: 129P2/OlaHsd * BALB/c	abnormal axon morphology	J:179606
	abnormal dentate gyrus morphology	J:179606
	abnormal gait	J:179606
	abnormal hippocampus stratum lacunosum morphology	J:179606
	abnormal neuron proliferation	J:179606
	decreased cerebellar granule cell number	J:179606
	decreased Purkinje cell number	J:179606
	increased brain size	J:179606
	increased brain weight	J:179606
	postnatal lethality, incomplete penetrance	J:179606
	premature death	J:179606
	tremors	J:179606
	weakness	J:179606
	weight loss	J:179606
Pura^tm1Kkh/Pura⁺ involves: 129	decreased cell proliferation	J:85759
	decreased DNA replication	J:85759
	postnatal growth retardation	J:85759
	seizures	J:85759
Pura^tm1Kkh/Pura^tm1Kkh involves: 129	abnormal brain white matter morphology	J:85759
	abnormal bronchiole epithelium morphology	J:85759
	abnormal cerebellar cortex morphology	J:85759
	abnormal cerebellar granule layer morphology	J:85759
	abnormal cerebellar molecular layer	J:85759
	abnormal cerebellum development	J:85759
	abnormal cerebellum external granule cell layer morphology	J:85759
	abnormal cerebellum morphology	J:85759
	abnormal gait	J:85759
	abnormal hippocampus morphology	J:85759
	abnormal nervous system tract morphology	J:85759
	abnormal posture	J:85759
	abnormal spleen morphology	J:85759
	abnormal tail movements	J:85759
	abnormal thymus morphology	J:85759
	cerebellum hypoplasia	J:85759
	decreased cell proliferation	J:85759
	decreased CNS synapse formation	J:85759
	decreased DNA replication	J:85759
	decreased locomotor activity	J:85759
	decreased neuron number	J:85759
	decreased neuronal precursor proliferation	J:85759
	decreased Purkinje cell number	J:85759
	decreased Purkinje cell size	J:85759
	decreased spleen weight	J:85759
	premature death	J:85759
	reticulocytopenia	J:85759
	seizures	J:85759
	slow postnatal weight gain	J:85759
	small spleen	J:85759
	tremors	J:85759

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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