Pdpn Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pdpn
podoplanin
MGI:103098

43 phenotypes from 6 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pdpn^tm1(cre)Mlkn/Pdpn^tm1(cre)Mlkn involves: 129S4/SvJae * C57BL/6	abnormal lymphatic vessel morphology	J:162815
	normal homeostasis/metabolism phenotype	J:162815
	intestinal edema	J:162815
Pdpn^tm1Acgg/Pdpn^tm1Acgg involves: 129S1/Sv * 129X1/SvJ * Swiss	abnormal coronary artery morphology	J:132132
	abnormal heart and great artery attachment	J:132132
	abnormal heart development	J:132132
	abnormal interventricular septum morphology	J:132132
	abnormal myocardial trabeculae morphology	J:132132
	abnormal myocardium compact layer morphology	J:132132
	abnormal myocardium layer morphology	J:132132
	decreased atrioventricular cushion size	J:132132
	detached epicardium	J:132132
	embryonic lethality during organogenesis, incomplete penetrance	J:132132
	lethality throughout fetal growth and development, incomplete penetrance	J:132132
	neonatal lethality, incomplete penetrance	J:132132
	thin myocardium	J:132132
Pdpn^{tm1b(EUCOMM)Wtsi}/Pdpn⁺ C57BL/6N-Pdpn^{tm1b(EUCOMM)Wtsi}/H	absent vibrissae	J:211773
	increased circulating calcium level	J:211773
	increased circulating cholesterol level	J:211773
Pdpn^{tm1b(EUCOMM)Wtsi}/Pdpn^{tm1b(EUCOMM)Wtsi} C57BL/6N-Pdpn^{tm1b(EUCOMM)Wtsi}/H	preweaning lethality, incomplete penetrance	J:211773
Pdpn^tm1Bwd/Pdpn^tm1Bwd either: (involves: Black Swiss) or (involves: C57BL/6)	increased fetal weight	J:109608
	neonatal lethality, complete penetrance	J:109608
	respiratory failure	J:109608
	normal skeleton phenotype	J:109608
Pdpn^tm1Mcws/Pdpn⁺ involves: 129S6/SvEvTac	abnormal lymphatic vessel morphology	J:94978
Pdpn^tm1Mcws/Pdpn⁺ involves: 129S6/SvEvTac	lymphangiectasis	J:94978
Pdpn^tm1Mcws/Pdpn^tm1Mcws involves: 129S6/SvEvTac	abnormal fetal growth/weight/body size	J:82687
	abnormal lung morphology	J:82687, J:119680
	abnormal lymph circulation	J:94978
	abnormal lymphatic vessel morphology	J:94978
	abnormal pulmonary alveolus morphology	J:82687, J:119680
	abnormal skin appearance	J:94978
	abnormal type I pneumocyte morphology	J:82687
	atelectasis	J:82687
	cyanosis	J:82687
	lethargy	J:82687
	lymphangiectasis	J:94978
	lymphedema	J:94978
	neonatal lethality, complete penetrance	J:82687
	respiratory failure	J:82687
	thick pulmonary interalveolar septum	J:82687
Pdpn^tm2.1Mlkn/Pdpn^tm2.1Mlkn Tg(CAG-cre/Esr1)5Amc/0 involves: 129 C57BL/6	abnormal lymphangiogenesis	J:235778
Pdpn^tm2.1Mlkn/Pdpn^tm2.1Mlkn Tg(CAG-cre/Esr1)5Amc/0 involves: C57BL/6 CBA	abnormal blood vessel morphology	J:205423
	abnormal lymph node morphology	J:205423
	absent peripheral lymph nodes	J:205423
	hemorrhage	J:205423
	increased vascular permeability	J:205423
Pdpn^tm2.1Mlkn/Pdpn^tm2.1Mlkn Tg(Pdgfrb-cre)9Rha/0 involves: C57BL/6	lymph node hemorrhage	J:205423

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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