About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Uchl1
ubiquitin carboxy-terminal hydrolase L1
MGI:103149
60 phenotypes from 5 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Uchl1gad-2J/Uchl1gad-2J
B6.Cg-Uchl1gad-2J/GrsrJ 		abnormal locomotor coordination J:161692
ataxia J:161692
neurodegeneration J:161692
paralysis J:161692
premature death J:161692
weight loss J:161692
Uchl1gad-J/Uchl1gad-J
involves: BALB/c * C57BL/6 		impaired coordination J:142436
premature death J:142436
weight loss J:142436
Uchl1gad/Uchl1gad
involves: CBA/Nga * RFM/Nga 		abnormal dorsal root ganglion morphology J:71819
abnormal gait J:71819
abnormal hindlimb morphology J:30954
abnormal medulla oblongata morphology J:30954
abnormal spinal cord dorsal column morphology J:30954
abnormal stationary movement J:30954
ataxia J:30954, J:71819
axon degeneration J:30954
axonal dystrophy J:71819
normal cardiovascular system phenotype J:30954
decreased body weight J:71819
normal digestive/alimentary phenotype J:30954
normal hematopoietic system phenotype J:30954
normal liver/biliary system phenotype J:30954
paralysis J:71819
premature death J:30954, J:71819
normal renal/urinary system phenotype J:30954
normal respiratory system phenotype J:30954
tremors J:30954
weight loss J:30954
Uchl1gad/Uchl1gad
Not Specified 		axon degeneration J:28526
motor neuron degeneration J:28526
Uchl1tm1b(EUCOMM)Hmgu/Uchl1+
C57BL/6N-Uchl1tm1b(EUCOMM)Hmgu/H 		abnormal spine curvature J:211773
hyperactivity J:211773
increased blood urea nitrogen level J:211773
increased circulating alkaline phosphatase level J:211773
increased mean platelet volume J:211773
increased startle reflex J:211773
Uchl1tm1Dgen/Uchl1tm1Dgen
B6.129P2-Uchl1tm1Dgen/Mmnc 		abnormal endplate potential J:156538
abnormal gait J:156538
abnormal miniature endplate potential J:156538
abnormal mitochondrial physiology J:361266
abnormal neuromuscular synapse morphology J:156538
abnormal oocyte morphology J:361266
abnormal ovarian follicle morphology J:361266
abnormal ovary morphology J:361266
abnormal ovary physiology J:361266
abnormal PNS synaptic transmission J:156538
abnormal synaptic plasticity J:156538
axon degeneration J:156538
decreased body size J:361266
decreased body weight J:361266
decreased circulating estradiol level J:361266
decreased neurotransmitter release J:156538
decreased oocyte number J:361266
decreased paired-pulse facilitation J:156538
decreased tertiary ovarian follicle number J:361266
female infertility J:361266
forelimb paralysis J:156538
hindlimb paralysis J:156538
impaired ovarian folliculogenesis J:361266
increased synaptic depression J:156538
kyphosis J:156538
limb grasping J:156538
maternal effect J:361266
motor neuron degeneration J:156538
premature death J:156538
prolonged diestrus J:361266
prolonged estrus J:361266
small ovary J:361266
Uchl1tm1Dgen/Uchl1tm1Dgen
involves: 129P2/OlaHsd * C57BL/6 		decreased grip strength J:207278
impaired coordination J:101679, J:207278
increased coping response J:101679
increased thermal nociceptive threshold J:101679
weight loss J:207278
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory