Dnase1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dnase1
deoxyribonuclease I
MGI:103157

13 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Dnase1^tm1Tmo/Dnase1⁺ involves: 129P2/OlaHsd * C57BL/6	enlarged spleen	J:62549
	glomerulonephritis	J:62549
	increased anti-nuclear antigen antibody level	J:62549
	kidney inflammation	J:62549
	premature death	J:62549
Dnase1^tm1Tmo/Dnase1^tm1Tmo involves: 129P2/OlaHsd * C57BL/6	enlarged spleen	J:62549
	glomerulonephritis	J:62549
	increased anti-nuclear antigen antibody level	J:62549
	increased susceptibility to systemic lupus erythematosus	J:62549
	kidney inflammation	J:62549
	premature death	J:62549
Dnase1^tm1Tmo/Dnase1^tm1Tmo involves: 129P2/OlaHsd * CD-1	decreased blood urea nitrogen level	J:110060
	decreased circulating creatinine level	J:110060
	decreased kidney apoptosis	J:110060
	decreased susceptibility to systemic lupus erythematosus	J:110060
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:110060
	kidney failure	J:110060
	renal tubular necrosis	J:110060

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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