Sod3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sod3
superoxide dismutase 3, extracellular
MGI:103181

11 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sod3^tm1Dgh/Sod3^tm1Dgh involves: C57BL/6	no abnormal phenotype detected	J:139655
Sod3^tm1Mrkl/Sod3^tm1Mrkl D1.129P2-Sod3^tm1Mrkl	autoimmune arthritis	J:106273
	increased susceptibility to induced arthritis	J:106273
	increased tumor necrosis factor secretion	J:106273
Sod3^tm1Mrkl/Sod3^tm1Mrkl involves: 129P2/OlaHsd * C57BL/6	increased susceptibility to induced morbidity/mortality	J:26851
Sod3^tm1Mrkl/Sod3^tm1Mrkl involves: 129P2/OlaHsd * C57BL/6	increased susceptibility to injury	J:26851
Sod3^tm1Svp/Sod3^tm1Svp involves: 129S6/SvEvTac * C57BL/6NTac	abnormal pulmonary artery morphology	J:285340
	decreased susceptibility to endotoxin shock	J:285340
	heart right ventricle hypertrophy	J:285340
	increased response of heart to induced stress	J:285340
	increased right ventricle systolic pressure	J:285340

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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