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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Uimc1
ubiquitin interaction motif containing 1
MGI:103185
15 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Uimc1Gt(RRN158)Byg/Uimc1Gt(RRN158)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal DNA repair J:188388
chromosome breakage J:188388
decreased tumor-free survival time J:188388
increased B cell derived lymphoma incidence J:188388
increased cellular sensitivity to gamma-irradiation J:188388
increased mortality induced by gamma-irradiation J:188388
increased tumor incidence J:188388
Uimc1tm1.2Amj/Uimc1tm1.2Amj
involves: BALB/cJ * C57BL/6 		abnormal cell cycle checkpoint function J:191827
decreased fibroblast proliferation J:191827
early cellular replicative senescence J:191827
increased B cell derived lymphoma incidence J:191827
increased incidence of tumors by chemical induction J:191827
increased incidence of tumors by ionizing radiation induction J:191827
increased lymphoma incidence J:191827
increased susceptibility to xenobiotic induced morbidity/mortality J:191827
increased T cell derived lymphoma incidence J:191827
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory