Mmp7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mmp7
matrix metallopeptidase 7
MGI:103189

20 phenotypes from 1 allele in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mmp7^tm1Lmm/Mmp7^tm1Lmm B6.129-Mmp7^tm1Lmm	abnormal PR interval	J:122893
	abnormal response to cardiac infarction	J:122893
	abnormal sinoatrial node conduction	J:122893
	decreased susceptibility to induced morbidity/mortality	J:122893
	diarrhea	J:149388
	normal digestive/alimentary phenotype	J:149388
	impaired wound healing	J:115243
	increased interleukin-1 beta secretion	J:149388
	increased susceptibility to induced colitis	J:149388
	increased susceptibility to xenobiotic induced morbidity/mortality	J:149388
	increased tumor incidence	J:105098
	intestinal ulcer	J:149388
	weight loss	J:149388
Mmp7^tm1Lmm/Mmp7^tm1Lmm involves: 129S1/Sv * 129X1/SvJ	decreased susceptibility to bacterial infection	J:153651
	decreased susceptibility to injury	J:76811
	normal immune system phenotype	J:55723
Mmp7^tm1Lmm/Mmp7^tm1Lmm involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal induced retina neovascularization	J:119224
Mmp7^tm1Lmm/Mmp7^tm1Lmm involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ	abnormal macrophage physiology	J:124841
	decreased tumor necrosis factor secretion	J:124841
	impaired macrophage chemotaxis	J:124841

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24