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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cdc25a
cell division cycle 25A
MGI:103198
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cdc25atm1Hpw/Cdc25atm1.1Hpw
Cdc25btm1Pjd/Cdc25btm1Pjd
Cdc25ctm1Hpw/Cdc25ctm1Hpw
Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 		abnormal small intestinal villus morphology J:145768
abnormal small intestine crypts of Lieberkuhn morphology J:145768
decreased small intestinal villus height J:145768
decreased small intestine length J:145768
premature death J:145768
weight loss J:145768
Cdc25atm1Hpw/Cdc25atm1.1Hpw
Cdc25btm1Pjd/Cdc25btm1Pjd
Cdc25ctm1Hpw/Cdc25ctm1Hpw
Tg(Vil1-cre/ERT2)23Syr/0
involves: 129X1/SvJ * C57BL/6 * DBA/2 		abnormal enterocyte differentiation J:169457
abnormal large intestine morphology J:169457
abnormal small intestinal crypt cell proliferation J:169457
abnormal small intestine crypts of Lieberkuhn morphology J:169457
abnormal small intestine morphology J:169457
decreased body weight J:169457
decreased small intestinal villus size J:169457
increased enterocyte apoptosis J:169457
postnatal lethality, incomplete penetrance J:169457
Cdc25atm1Hpw/Cdc25atm1.1Hpw
Cdc25btm1Pjd/Cdc25btm1Pjd
Tg(Vil1-cre/ERT2)23Syr/0
involves: 129X1/SvJ * C57BL/6 * DBA/2 		abnormal enterocyte differentiation J:169457
abnormal large intestine morphology J:169457
abnormal small intestinal crypt cell proliferation J:169457
abnormal small intestine crypts of Lieberkuhn morphology J:169457
abnormal small intestine morphology J:169457
decreased body weight J:169457
decreased small intestinal villus size J:169457
increased enterocyte apoptosis J:169457
postnatal lethality, incomplete penetrance J:169457
Cdc25atm1Hpw/Cdc25atm1.1Hpw
Cdc25ctm1Hpw/Cdc25ctm1Hpw
Tg(Vil1-cre/ERT2)23Syr/0
involves: 129X1/SvJ * C57BL/6 * DBA/2 		normal digestive/alimentary phenotype J:169457
normal growth/size/body region phenotype J:169457
Cdc25atm1Kiyo/Cdc25a+
Tg(MMTV-Myc)141-3Led/?
involves: 129/Sv * C57BL/6 * C57BL/6J * CD-1 		normal neoplasm J:123144
Cdc25atm1Kiyo/Cdc25a+
Tg(MMTV-vHaras)SH1Led/?
involves: 129/Sv * C57BL/6 * C57BL/6J * CD-1 		decreased incidence of induced tumors J:123144
Cdc25atm1Kiyo/Cdc25a+
Tg(MMTV-Erbb2)NK1Mul/?
involves: 129/Sv * C57BL/6 * FVB/N 		decreased cell proliferation J:123144
decreased incidence of induced tumors J:123144
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory