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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Zbtb16
zinc finger and BTB domain containing 16
MGI:103222
87 phenotypes from 10 alleles in 14 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tg(Cd4-Zbtb16)1797Aben/?
C57BL/6-Tg(Cd4-Zbtb16)1797Aben 		decreased CD4-positive, alpha-beta T cell number J:139690
increased CD4-positive, alpha-beta memory T cell number J:139690
increased T-helper 2 cell number J:139690
Zbtb167t/Zbtb167t
involves: C3HeB/FeJ * C57BL/6J 		abnormal digit morphology J:160477
abnormal fibula morphology J:160477
abnormal hindlimb zeugopod morphology J:160477
abnormal long bone morphology J:160477
abnormal metatarsal bone morphology J:160477
abnormal talus morphology J:160477
abnormal tibia morphology J:160477
abnormal xiphoid process morphology J:160477
absent fibula J:160477
ectopic digits J:160477
fused metatarsal bones J:160477
increased diameter of fibula J:160477
increased rib number J:160477
interdigital webbing J:160477
oligodactyly J:160477
polydactyly J:160477
normal reproductive system phenotype J:160477
sacral vertebral transformation J:160477
Zbtb16em1(IMPC)Mbp/Zbtb16em1(IMPC)Mbp
C57BL/6NCrl-Zbtb16em1(IMPC)Mbp/MbpMmucd 		abnormal auditory brainstem response J:211773
abnormal autopod morphology J:211773
abnormal brain morphology J:211773
abnormal digit morphology J:211773
abnormal gait J:211773
abnormal hindlimb morphology J:211773
abnormal liver morphology J:211773
abnormal optic disk morphology J:211773
abnormal spleen morphology J:211773
abnormal testis morphology J:211773
abnormal vitreous body morphology J:211773
cataract J:211773
cornea opacity J:211773
decreased body length J:211773
decreased brain size J:211773
decreased prepulse inhibition J:211773
decreased total body fat amount J:211773
hyperactivity J:211773
increased freezing behavior J:211773
increased lean body mass J:211773
small liver J:211773
small spleen J:211773
small testis J:211773
Zbtb16lu-3J/Zbtb16lu-3J
B6;D2-a Ces1ce Zbtb16lu-3J/BrkJ 		abnormal limb morphology J:150401
hemimelia J:150401
Zbtb16lu-Sfd/Zbtb16+
involves: C57BL/6 		polydactyly J:109970
polyphalangy J:109970
Zbtb16lu-Sfd/Zbtb16+
involves: C57BL/6 * Swiss 		polydactyly J:109970
polyphalangy J:109970
Zbtb16lu-Sfd/Zbtb16lu-Sfd
involves: C57BL/6 		abnormal digit morphology J:109970
increased diameter of fibula J:109970
male infertility J:109970
oligodactyly J:109970
polydactyly J:109970
polyphalangy J:109970
short tibia J:109970
Zbtb16lu-Sfd/Zbtb16lu-Sfd
involves: C57BL/6 * Swiss 		abnormal digit morphology J:109970
increased diameter of fibula J:109970
kinked tail J:109970
male infertility J:109970
oligodactyly J:109970
polydactyly J:109970
polyphalangy J:109970
short tibia J:109970
Zbtb16lu/Zbtb16+
B10.C3-Zbtb16lu 		increased presacral vertebrae number J:13069
increased rib number J:13069
increased sternebra number J:13069
polydactyly J:13069
polyphalangy J:13069
Zbtb16lu/Zbtb16+
involves: C3H/He 		increased presacral vertebrae number J:13069
increased rib number J:13069
increased sternebra number J:13069
polyphalangy J:13069
Zbtb16lu/Zbtb16lu
B6.C3-Zbtb16Lu 		azoospermia J:89934
decreased male germ cell number J:89934
small testis J:89934
Zbtb16lu/Zbtb16lu
B6.C3-Zbtb16lu/J 		decreased NK T cell number J:139690
Zbtb16lu/Zbtb16lu
B10.C3-Zbtb16lu 		abnormal tarsal bone morphology J:13069
increased presacral vertebrae number J:13069
increased rib number J:13069
increased sternebra number J:13069
kinked tail J:13069
long fibula J:13069
polydactyly J:13069
polyphalangy J:13069
short tibia J:13069
Zbtb16lu/Zbtb16lu
involves: C3H/He 		abnormal tarsal bone morphology J:13069
bowed fibula J:13069
brachyphalangia J:13069
increased presacral vertebrae number J:13069
increased rib number J:13069
increased sternebra number J:13069
kinked tail J:13069
long fibula J:13069
polydactyly J:13069
polyphalangy J:13069
short tibia J:13069
Zbtb16lu/Zbtb16lu
involves: C3H/He * C57BL/6 		seminiferous tubule degeneration J:160477
Zbtb16lu/Zbtb16lu
Not Specified 		azoospermia J:5206
male infertility J:5206
Zbtb16pnky/Zbtb16pnky
CBA/CaJAnu-Zbtb16pnky/Apb 		abnormal hindlimb morphology J:104190
polydactyly J:104190
reduced male fertility J:104190
short hindlimb J:104190
Zbtb16tm1Geno/Zbtb16tm1Geno
Not Specified 		abnormal bone marrow cell physiology J:199097
abnormal DNA methylation J:199097
abnormal epigenetic regulation of gene expression J:199097
abnormal male germ cell apoptosis J:199097
abnormal testis morphology J:199097
Zbtb16tm1Ppp/Zbtb16tm1Ppp
involves: 129S1/Sv 		abnormal axial skeleton morphology J:62547
abnormal fibula morphology J:62547
abnormal forelimb morphology J:62547
abnormal hindlimb morphology J:62547
abnormal metatarsal bone morphology J:62547
abnormal patella morphology J:62547
abnormal spermatogenesis J:91129
abnormal spermatogonia morphology J:91129
abnormal spermatogonia proliferation J:91129
abnormal talus morphology J:62547
abnormal tarsal bone morphology J:62547
abnormal tibia morphology J:62547
absent fibula J:62547
absent patella J:62547
asthenozoospermia J:91129
decreased caudal vertebrae number J:62547
ectopic digits J:62547
fused metatarsal bones J:62547
normal hematopoietic system phenotype J:65878
hindlimb oligodactyly J:62547
increased circulating testosterone level J:91129
increased diameter of fibula J:62547
increased Leydig cell number J:91129
increased male germ cell apoptosis J:91129
increased rib number J:62547
increased thoracic vertebrae number J:62547
kinked tail J:62547
lumbar vertebral transformation J:62547
oligozoospermia J:91129
polydactyly J:62547
sacral vertebral transformation J:62547
seminiferous tubule degeneration J:91129
short hindlimb J:62547
short tail J:62547
small testis J:91129
testicular atrophy J:91129
thoracic vertebral transformation J:62547
vertebral transformation J:62547
xiphoid process foramen J:62547
Zbtb16tm2Geno/Zbtb16tm2Geno
Not Specified 		abnormal bone marrow cell physiology J:199097
abnormal DNA methylation J:199097
normal reproductive system phenotype J:199097
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory