Slk Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slk
STE20-like kinase
MGI:103241

27 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slk^em1(IMPC)Bay/Slk⁺ C57BL/6N-Slk^em1(IMPC)Bay/BayMmucd	abnormal embryo size	J:211773
	embryonic growth retardation	J:211773
	increased vertical activity	J:211773
Slk^em1(IMPC)Bay/Slk^em1(IMPC)Bay C57BL/6N-Slk^em1(IMPC)Bay/BayMmucd	prenatal lethality	J:211773
	preweaning lethality, complete penetrance	J:211773
Slk^{Gt(BC0415)Wtsi}/Slk^{Gt(BC0415)Wtsi} involves: 129P2/OlaHsd * FVB/N	abnormal blood vessel morphology	J:211339
	abnormal brain development	J:211339
	abnormal dorsal root ganglion morphology	J:211339
	abnormal embryo development	J:211339
	abnormal enzyme/coenzyme activity	J:211339
	abnormal eye development	J:211339
	abnormal limb development	J:211339
	abnormal myogenesis	J:211339
	abnormal placenta development	J:211339
	abnormal placenta junctional zone morphology	J:211339
	abnormal placenta labyrinth morphology	J:211339
	abnormal placenta vasculature	J:211339
	abnormal placental labyrinth vasculature morphology	J:211339
	decreased embryo size	J:211339
	decreased fibroblast proliferation	J:211339
	decreased neuronal precursor cell number	J:211339
	disorganized dorsal root ganglion	J:211339
	embryonic growth retardation	J:211339
	hemorrhage	J:211339
	increased brain size	J:211339
	increased embryonic tissue cell apoptosis	J:211339
	increased placenta apoptosis	J:211339
	lethality throughout fetal growth and development, complete penetrance	J:211339

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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