Fgl2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fgl2
fibrinogen-like protein 2
MGI:103266

33 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fgl2^tm1Pam/Fgl2⁺ involves: 129X1/SvJ * C57BL/6	decreased susceptibility to Coronaviridae infection	J:99453
Fgl2^tm1Pam/Fgl2^tm1Pam B6.129X1-Fgl2^tm1Pam	abnormal B cell physiology	J:130895
	abnormal dendritic cell physiology	J:130895
	abnormal glomerular mesangium morphology	J:130895
	abnormal Peyer's patch follicle morphology	J:130895
	abnormal regulatory T cell physiology	J:130895
	abnormal renal glomerulus morphology	J:130895
	abnormal T cell physiology	J:130895
	abnormal urine albumin level	J:130895
	decreased body size	J:130895
	decreased dendritic cell apoptosis	J:130895
	decreased kidney weight	J:130895
	decreased Peyer's patch number	J:130895
	decreased susceptibility to Coronaviridae infection	J:99453
	decreased susceptibility to Coronaviridae infection induced morbidity/mortality	J:99453
	embryonic lethality between somite formation and embryo turning, incomplete penetrance	J:99453
	enlarged spleen	J:130895
	glomerulonephritis	J:130895
	hematuria	J:130895
	increased circulating creatinine level	J:130895
	increased dendritic cell number	J:130895
	increased IgA level	J:130895
	increased IgG level	J:130895
	increased IgM level	J:130895
	increased regulatory T cell number	J:130895
	increased T cell proliferation	J:130895
	kidney hemorrhage	J:130895
	renal glomerulus fibrosis	J:130895
	small kidney	J:130895
	weight loss	J:130895
Fgl2^tm1Pam/Fgl2^tm1Pam involves: 129X1/SvJ * C57BL/6	abnormal blood coagulation	J:99453
	decreased susceptibility to Coronaviridae infection	J:99453
	decreased susceptibility to Coronaviridae infection induced morbidity/mortality	J:99453
	embryonic lethality between somite formation and embryo turning, incomplete penetrance	J:99453
	hemorrhage	J:99453
Fgl2^tm1Pam/Fgl2^tm1Pam involves: 129X1/SvJ * C57BL/6J	increased length of allograft survival	J:98997
Fgl2^tm1Stsm/Fgl2^tm1Stsm C57BL/6-Fgl2^tm1Stsm	normal immune system phenotype	J:88648

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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