Tfeb Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tfeb
transcription factor EB
MGI:103270

15 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tfeb^em1Xinli/Tfeb^em1Xinli involves: C57BL/6J	normal growth/size/body region phenotype	J:342735
	increased susceptibility to bacterial infection induced morbidity/mortality	J:342735
	normal mortality/aging	J:342735
Tfeb^{Gt(PT1-ATG)213Wrst}/Tfeb^{Gt(PT1-ATG)213Wrst} involves: 129S1/Sv * 129X1/SvJ * CD-1	no abnormal phenotype detected	J:47966
Tfeb^{tm1a(EUCOMM)Wtsi}/Tfeb⁺ C57BL/6N-Tfeb^{tm1a(EUCOMM)Wtsi}/Bay	decreased circulating alkaline phosphatase level	J:211773
	decreased hemoglobin content	J:211773
	increased lean body mass	J:211773
Tfeb^{tm1a(EUCOMM)Wtsi}/Tfeb^{tm1a(EUCOMM)Wtsi} C57BL/6N-Tfeb^{tm1a(EUCOMM)Wtsi}/Bay	preweaning lethality, complete penetrance	J:211773
Tfeb^{tm1b(EUCOMM)Wtsi}/Tfeb⁺ C57BL/6N-Tfeb^{tm1b(EUCOMM)Wtsi}/Bay	decreased lean body mass	J:211773
	increased total body fat amount	J:211773
	trunk curl	J:211773
	unresponsive to tactile stimuli	J:211773
Tfeb^{tm1b(EUCOMM)Wtsi}/Tfeb^{tm1b(EUCOMM)Wtsi} C57BL/6N-Tfeb^{tm1b(EUCOMM)Wtsi}/Bay	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Tfeb^tm1Est/Tfeb^tm1Est involves: 129S1/Sv	abnormal placenta morphology	J:89821
Tfeb^tm1Est/Tfeb^tm1Est involves: 129S1/Sv	prenatal lethality	J:89821

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24