Tfeb Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tfeb
transcription factor EB
MGI:103270

15 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tfeb^em1Xinli/Tfeb^em1Xinli involves: C57BL/6J	normal growth/size/body region phenotype	J:342735
	increased susceptibility to bacterial infection induced morbidity/mortality	J:342735
	normal mortality/aging	J:342735
Tfeb^{Gt(PT1-ATG)213Wrst}/Tfeb^{Gt(PT1-ATG)213Wrst} involves: 129S1/Sv * 129X1/SvJ * CD-1	no abnormal phenotype detected	J:47966
Tfeb^{tm1a(EUCOMM)Wtsi}/Tfeb⁺ C57BL/6N-Tfeb^{tm1a(EUCOMM)Wtsi}/Bay	decreased circulating alkaline phosphatase level	J:211773
	decreased hemoglobin content	J:211773
	increased lean body mass	J:211773
Tfeb^{tm1a(EUCOMM)Wtsi}/Tfeb^{tm1a(EUCOMM)Wtsi} C57BL/6N-Tfeb^{tm1a(EUCOMM)Wtsi}/Bay	preweaning lethality, complete penetrance	J:211773
Tfeb^{tm1b(EUCOMM)Wtsi}/Tfeb⁺ C57BL/6N-Tfeb^{tm1b(EUCOMM)Wtsi}/Bay	decreased lean body mass	J:211773
	increased total body fat amount	J:211773
	trunk curl	J:211773
	unresponsive to tactile stimuli	J:211773
Tfeb^{tm1b(EUCOMM)Wtsi}/Tfeb^{tm1b(EUCOMM)Wtsi} C57BL/6N-Tfeb^{tm1b(EUCOMM)Wtsi}/Bay	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Tfeb^tm1Est/Tfeb^tm1Est involves: 129S1/Sv	abnormal placenta morphology	J:89821
Tfeb^tm1Est/Tfeb^tm1Est involves: 129S1/Sv	prenatal lethality	J:89821

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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