About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Relb
avian reticuloendotheliosis viral (v-rel) oncogene related B
MGI:103289
88 phenotypes from 3 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Relbshep/Relbshep
A;C-Relbshep/GrsrJ 		abnormal circulating protein level J:171971
anemia J:171971
decreased body size J:171971
decreased body weight J:171971
decreased circulating amylase level J:171971
decreased circulating serum albumin level J:171971
decreased circulating total protein level J:171971
decreased liver function J:171971
lethality at weaning, complete penetrance J:171971
liver cirrhosis J:171971
liver failure J:171971
liver inflammation J:171971
pale liver J:171971
preweaning lethality, incomplete penetrance J:171971
thin tail J:171971
Relbtm1.1Fwei/Relbtm1.1Fwei
Tg(Cd4-cre)1Cwi/0
involves: C57BL/6 * DBA/2 		normal immune system phenotype J:169863
Relbtm1.1Fwei/Relbtm1.1Fwei
Tg(Lck-cre)I57Jxm/0
involves: ICR 		abnormal gamma-delta T cell morphology J:169863
decreased interleukin-17 secretion J:169863
normal immune system phenotype J:169863
increased susceptibility to bacterial infection J:169863
Relbtm1Brv/Relbtm1Brv
either: (involves: 129S2/SvPas) or (involves: C57BL/6) or (involves: 129S2/SvPas * C57BL/6) 		abnormal epidermis stratum corneum morphology J:63950
abnormal keratinocyte apoptosis J:63950
abnormal keratinocyte physiology J:63950
acanthosis J:63950
alopecia J:63950
dermatitis J:63950
epidermal hyperplasia J:63950
hyperkeratosis J:63950
increased eosinophil cell number J:63950
increased keratinocyte proliferation J:63950
increased respiratory mucosa goblet cell number J:63950
lung inflammation J:63950
mixed cellular infiltration to dermis J:63950
pathological neovascularization J:63950
reddish skin J:63950
scaly skin J:63950
thick dermal layer J:63950
thick epidermis J:63950
thick skin J:63950
Relbtm1Brv/Relbtm1Brv
involves: 129S2/SvPas 		abnormal gamma-delta T cell morphology J:169863
decreased dendritic cell number J:85808
spleen hyperplasia J:85808
Relbtm1Brv/Relbtm1Brv
involves: 129S2/SvPas * C57BL/6 		abnormal bile duct morphology J:22675
abnormal cell-mediated immunity J:22675
abnormal cytokine level J:40630
abnormal cytotoxic T cell physiology J:40630
abnormal definitive hematopoiesis J:22675
abnormal erythropoiesis J:22675
abnormal hepatobiliary system morphology J:22675
abnormal humoral immune response J:40630
abnormal immune system organ morphology J:22675
abnormal immune system physiology J:22675, J:40630
abnormal immunoglobulin level J:40630
abnormal interferon level J:40630
abnormal interleukin level J:40630
abnormal lymph node morphology J:22675
abnormal macrophage physiology J:40630
abnormal mesenteric lymph node morphology J:22675
abnormal proerythroblast morphology J:22675
abnormal tumor necrosis factor level J:40630
amyloidosis J:22675
decreased B cell proliferation J:40630
decreased dendritic cell number J:22675
decreased spleen white pulp amount J:22675
decreased susceptibility to type IV hypersensitivity reaction J:22675
decreased T cell number J:22675
disheveled coat J:22675
distended abdomen J:22675
epididymis inflammation J:22675
extramedullary hematopoiesis J:22675
hunched posture J:22675
impaired neutrophil phagocytosis J:40630
increased bone marrow cell number J:22675
increased IgE level J:40630
increased IgM level J:40630
increased spleen red pulp amount J:22675
increased spleen weight J:22675
increased susceptibility to bacterial infection J:40630
increased susceptibility to Riboviria infection J:40630
intestinal inflammation J:22675
liver fibrosis J:22675
liver inflammation J:22675
lung inflammation J:22675
myeloid hyperplasia J:22675
myositis J:22675
ovary inflammation J:22675
premature death J:22675
pulmonary alveolar hemorrhage J:22675
pulmonary fibrosis J:22675
reduced fertility J:22675
salivary gland inflammation J:22675
stomach inflammation J:22675
thymus atrophy J:22675
thymus hypoplasia J:22675
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory