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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Relb
avian reticuloendotheliosis viral (v-rel) oncogene related B
MGI:103289
88 phenotypes from 3 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Relbshep/Relbshep
A;C-Relbshep/GrsrJ 		abnormal circulating protein level J:171971
anemia J:171971
decreased body size J:171971
decreased body weight J:171971
decreased circulating amylase level J:171971
decreased circulating serum albumin level J:171971
decreased circulating total protein level J:171971
decreased liver function J:171971
lethality at weaning, complete penetrance J:171971
liver cirrhosis J:171971
liver failure J:171971
liver inflammation J:171971
pale liver J:171971
preweaning lethality, incomplete penetrance J:171971
thin tail J:171971
Relbtm1.1Fwei/Relbtm1.1Fwei
Tg(Cd4-cre)1Cwi/0
involves: C57BL/6 * DBA/2 		normal immune system phenotype J:169863
Relbtm1.1Fwei/Relbtm1.1Fwei
Tg(Lck-cre)I57Jxm/0
involves: ICR 		abnormal gamma-delta T cell morphology J:169863
decreased interleukin-17 secretion J:169863
normal immune system phenotype J:169863
increased susceptibility to bacterial infection J:169863
Relbtm1Brv/Relbtm1Brv
either: (involves: 129S2/SvPas) or (involves: C57BL/6) or (involves: 129S2/SvPas * C57BL/6) 		abnormal epidermis stratum corneum morphology J:63950
abnormal keratinocyte apoptosis J:63950
abnormal keratinocyte physiology J:63950
acanthosis J:63950
alopecia J:63950
dermatitis J:63950
epidermal hyperplasia J:63950
hyperkeratosis J:63950
increased eosinophil cell number J:63950
increased keratinocyte proliferation J:63950
increased respiratory mucosa goblet cell number J:63950
lung inflammation J:63950
mixed cellular infiltration to dermis J:63950
pathological neovascularization J:63950
reddish skin J:63950
scaly skin J:63950
thick dermal layer J:63950
thick epidermis J:63950
thick skin J:63950
Relbtm1Brv/Relbtm1Brv
involves: 129S2/SvPas 		abnormal gamma-delta T cell morphology J:169863
decreased dendritic cell number J:85808
spleen hyperplasia J:85808
Relbtm1Brv/Relbtm1Brv
involves: 129S2/SvPas * C57BL/6 		abnormal bile duct morphology J:22675
abnormal cell-mediated immunity J:22675
abnormal cytokine level J:40630
abnormal cytotoxic T cell physiology J:40630
abnormal definitive hematopoiesis J:22675
abnormal erythropoiesis J:22675
abnormal hepatobiliary system morphology J:22675
abnormal humoral immune response J:40630
abnormal immune system organ morphology J:22675
abnormal immune system physiology J:22675, J:40630
abnormal immunoglobulin level J:40630
abnormal interferon level J:40630
abnormal interleukin level J:40630
abnormal lymph node morphology J:22675
abnormal macrophage physiology J:40630
abnormal mesenteric lymph node morphology J:22675
abnormal proerythroblast morphology J:22675
abnormal tumor necrosis factor level J:40630
amyloidosis J:22675
decreased B cell proliferation J:40630
decreased dendritic cell number J:22675
decreased spleen white pulp amount J:22675
decreased susceptibility to type IV hypersensitivity reaction J:22675
decreased T cell number J:22675
disheveled coat J:22675
distended abdomen J:22675
epididymis inflammation J:22675
extramedullary hematopoiesis J:22675
hunched posture J:22675
impaired neutrophil phagocytosis J:40630
increased bone marrow cell number J:22675
increased IgE level J:40630
increased IgM level J:40630
increased spleen red pulp amount J:22675
increased spleen weight J:22675
increased susceptibility to bacterial infection J:40630
increased susceptibility to Riboviria infection J:40630
intestinal inflammation J:22675
liver fibrosis J:22675
liver inflammation J:22675
lung inflammation J:22675
myeloid hyperplasia J:22675
myositis J:22675
ovary inflammation J:22675
premature death J:22675
pulmonary alveolar hemorrhage J:22675
pulmonary fibrosis J:22675
reduced fertility J:22675
salivary gland inflammation J:22675
stomach inflammation J:22675
thymus atrophy J:22675
thymus hypoplasia J:22675
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory