Apobec1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apobec1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
MGI:103298

20 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Apobec1^{em1(IMPC)Ccpcz}/Apobec1^{em1(IMPC)Ccpcz} C57BL/6NCrl-Apobec1^{em1(IMPC)Ccpcz}/Ccpcz	abnormal digit morphology	J:211773
	abnormal heart morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal thymus morphology	J:211773
	decreased startle reflex	J:211773
	enlarged heart	J:211773
	enlarged spleen	J:211773
	enlarged thymus	J:211773
	hyperactivity	J:211773
	small spleen	J:211773
	small testis	J:211773
Apobec1^tm1Chan/Apobec1^tm1Chan involves: 129S4/SvJae * C57BL/6	decreased circulating HDL cholesterol level	J:36051
Apobec1^tm1Ddsn/Apobec1^tm1Ddsn B6.129S4-Apobec1^tm1Ddsn	abnormal lipid homeostasis	J:108052
Apobec1^tm1Ddsn/Apobec1^tm1Ddsn B6.129S4-Apobec1^tm1Ddsn	abnormal triglyceride level	J:108052
Apobec1^tm1Ddsn/Apobec1^tm1Ddsn involves: 129S4/SvJae	no abnormal phenotype detected	J:32731
Apobec1^tm1Ishi/Apobec1^tm1Ishi involves: 129S7/SvEvBrd * C57BL/6	decreased circulating cholesterol level	J:41982
	increased cholesterol level	J:41982
Apobec1^tm1Rub/Apobec1^tm1Rub involves: C57BL/6 * DBA	abnormal lipid homeostasis	J:74021
	decreased circulating HDL cholesterol level	J:74021
	increased circulating LDL cholesterol level	J:74021

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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