Apobec1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apobec1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
MGI:103298

17 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apobec1^tm1Chan/Apobec1^tm1Chan Apoe^tm1Unc/Apoe^tm1Unc involves: 129P2/OlaHsd * 129S4/SvJae	abnormal circulating cholesterol level	J:48202
	decreased circulating cholesterol level	J:48202
	increased circulating cholesterol level	J:48202
	increased circulating triglyceride level	J:48202
Apobec1^tm1Chan/Apobec1^tm1Chan Ldlr^tm1Her/Ldlr^tm1Her involves: 129S4/SvJae * 129S7/SvEvBrd	abnormal circulating cholesterol level	J:48202
	decreased circulating triglyceride level	J:48202
	increased circulating cholesterol level	J:48202
	increased circulating triglyceride level	J:48202
Apobec1^tm1Chan/Apobec1^tm1Chan Tg(CETP)5203Tall/0 involves: 129S4/SvJae * C57BL/6J * CBA/J	abnormal circulating cholesterol level	J:48202
	decreased circulating HDL cholesterol level	J:48202
	decreased circulating triglyceride level	J:48202
	increased circulating cholesterol level	J:48202
	increased circulating triglyceride level	J:48202
Apobec1^tm1Ddsn/Apobec1^tm1Ddsn Fgg^tm1Fjc/Fgg^tm1Fjc Ldlr^tm1Her/Ldlr^tm1Her B6.129-Fgg^tm1Fjc Apobec1^tm1Ddsn Ldlr^tm1Her	abnormal blood coagulation	J:132734
	atherosclerotic lesions	J:132734
	increased circulating LDL cholesterol level	J:132734
	postnatal lethality, incomplete penetrance	J:135942
Apobec1^tm1Ddsn/Apobec1^tm1Ddsn Ldlr^tm1Her/Ldlr^tm1Her B6.129-Apobec1^tm1Ddsn Ldlr^tm1Her	abnormal blood coagulation	J:132734
	atherosclerotic lesions	J:132734
	decreased partial thromboplastin time	J:132734
	decreased prothrombin time	J:132734
	increased circulating antithrombin level	J:132734
	increased circulating LDL cholesterol level	J:132734
	increased circulating prothrombin level	J:132734
Apobec1^tm1Ddsn/Apobec1^tm1Ddsn Ldlr^tm1Her/Ldlr^tm1Her involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6	atherosclerotic lesions	J:49125
	increased circulating cholesterol level	J:49125
	increased circulating LDL cholesterol level	J:49125
	increased circulating triglyceride level	J:49125
Apobec1^tm1Ishi/Apobec1^tm1Ishi Apoe^tm1Unc/Apoe^tm1Unc involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6	decreased circulating cholesterol level	J:41982
	increased circulating triglyceride level	J:41982
Apobec1^tm1Rub/Apobec1^tm1Rub Apoe^{tm1(APOE2)Mae}/Apoe^{tm1(APOE2)Mae} involves: 129P2/OlaHsd * C57BL/6	decreased circulating cholesterol level	J:79196
	decreased circulating LDL cholesterol level	J:79196
	increased circulating HDL cholesterol level	J:79196
	increased circulating triglyceride level	J:79196
	increased circulating VLDL triglyceride level	J:79196

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24