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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Bmp7
bone morphogenetic protein 7
MGI:103302
90 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Bmp2tm1Brd/Bmp2+
Bmp7tm1Kry/Bmp7+
Not Specified 		normal skeleton phenotype J:48538
Bmp2tm1Cjt/Bmp2+
Bmp7tm1Rob/Bmp7+
Tg(Prrx1-cre)1Cjt/0
involves: 129S/SvEv * C57BL/6 * SJL 		no abnormal phenotype detected J:118257
Bmp2tm1Cjt/Bmp2+
Bmp7tm1Rob/Bmp7tm1Rob
Tg(Prrx1-cre)1Cjt/0
involves: 129S/SvEv * C57BL/6 * SJL 		no abnormal phenotype detected J:118257
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp7tm1Rob/Bmp7+
Tg(Prrx1-cre)1Cjt/0
involves: 129S/SvEv * C57BL/6 * SJL 		abnormal scapula morphology J:118257
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp7tm1Rob/Bmp7tm1Rob
Tg(Prrx1-cre)1Cjt/0
involves: 129S/SvEv * C57BL/6 * SJL 		abnormal appendicular skeleton morphology J:118257
abnormal fibula morphology J:118257
abnormal phalanx morphology J:118257
abnormal scapula morphology J:118257
Bmp2tm1Jfm/Bmp2+
Bmp4tm1Jfm/Bmp4+
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		absent alisphenoid bone J:181229
cleft palate J:181229
decreased tympanic ring size J:181229
small temporal bone squamous part J:181229
Bmp2tm1Jfm/Bmp2+
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		cleft palate J:181229
decreased tympanic ring size J:181229
small alisphenoid bone J:181229
small nasal bone J:181229
small temporal bone squamous part J:181229
small zygomatic bone J:181229
Bmp2tm1Jfm/Bmp2+
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		abnormal tympanic ring morphology J:181229
cleft palate J:181229
small interparietal bone J:181229
small nasal bone J:181229
small temporal bone squamous part J:181229
small zygomatic bone J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4+
Bmp7tm1Jfm/Bmp7+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		absent alisphenoid bone J:181229
absent mandibular coronoid process J:181229
absent zygomatic bone J:181229
cleft palate J:181229
small nasal bone J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4+
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		abnormal temporal bone squamous part morphology J:181229
abnormal tympanic ring morphology J:181229
absent alisphenoid bone J:181229
absent mandibular coronoid process J:181229
absent zygomatic bone J:181229
cleft palate J:181229
small nasal bone J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		abnormal interparietal bone morphology J:181229
abnormal mandibular angle morphology J:181229
abnormal mandibular condyloid process morphology J:181229
abnormal nasal bone morphology J:181229
absent alisphenoid bone J:181229
absent mandibular coronoid process J:181229
absent maxilla J:181229
absent temporal bone squamous part J:181229
absent tympanic ring J:181229
absent zygomatic bone J:181229
cleft palate J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		abnormal craniofacial bone morphology J:181229
abnormal interparietal bone morphology J:181229
abnormal mandible morphology J:181229
abnormal nasal bone morphology J:181229
absent alisphenoid bone J:181229
absent mandibular angle J:181229
absent mandibular condyloid process J:181229
absent mandibular coronoid process J:181229
absent maxilla J:181229
absent temporal bone squamous part J:181229
absent tympanic ring J:181229
absent zygomatic bone J:181229
cleft palate J:181229
large anterior fontanelle J:181229
Bmp4tm1Blh/Bmp4+
Bmp7tm1Kry/Bmp7+
involves: 129S2/SvPas * 129S7/SvEvBrd 		abnormal digit morphology J:48538
abnormal sternum morphology J:48538
abnormal thoracic cage morphology J:48538
asymmetric rib joints J:48538
normal growth/size/body region phenotype J:48538
polydactyly J:48538
rib fusion J:48538
split xiphoid process J:48538
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		abnormal mandible morphology J:181229
cleft palate J:181229
decreased tympanic ring size J:181229
large anterior fontanelle J:181229
small temporal bone squamous part J:181229
Bmp4tm4Blh/Bmp4+
Bmp7tm1.1Dgra/Bmp7tm1.1Dgra
Hoxa3tm1(cre)Moon/Hoxa3+
involves: 129S6/SvEvTac * C57BL/6NTac 		absent urinary bladder J:192045
anal stenosis J:192045
sirenomelia J:192045
Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
involves: C3H/HeJ * C57BL/6 		abnormal distal convoluted tubule morphology J:38288
abnormal kidney development J:38288
abnormal retina pigment epithelium morphology J:38288
abnormal retina pigmentation J:38288
abnormal sacral vertebrae morphology J:38288
abnormal skeleton morphology J:38288
abnormal vertebrae morphology J:38288
aphakia J:38288
basisphenoid bone foramen J:38288
decreased birth weight J:38288
decreased bone mineral density J:38288
decreased lumbar vertebrae number J:38288
decreased nephron number J:38288
delayed bone ossification J:38288
eyelids fail to open J:38288
fusion of vertebral bodies J:38288
impaired coordination J:38288
kinked tail J:38288
neonatal lethality, incomplete penetrance J:38288
polycystic kidney J:38288
polydactyly J:38288
premature death J:38288
rib fusion J:38288
small kidney J:38288
tremors J:38288
xiphoid process foramen J:38288
Bmp7tm1Kry/Bmp7tm1Kry
Nogtm1Amc/Nogtm1Amc
either: (involves: 129S1/Sv * C57BL/6) or (involves: 129S1/Sv * CD-1 * ICR) 		normal digestive/alimentary phenotype J:118341
normal nervous system phenotype J:118341
prenatal lethality, complete penetrance J:118341
Bmp7tm1Rob/Bmp7+
Bmp8atm1Blh/Bmp8atm1Blh
involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss 		abnormal epididymis morphology J:78867
decreased testis weight J:78867
Bmp7tm1Rob/Bmp7+
Bmp8atm1Blh/Bmp8atm1Blh
involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss * C57BL/6 		abnormal epididymis morphology J:78867
abnormal male germ cell morphology J:78867
abnormal spermatogenesis J:78867
epididymis degeneration J:78867
epididymis epithelium degeneration J:78867
granulomatous inflammation J:78867
male infertility J:78867
Bmp7tm1Rob/Bmp7+
Fbn2tm1Rmz/Fbn2+
either: (involves: 129/Sv * 129S/SvEv) or (involves: 129/Sv * 129S/SvEv * C57BL/6J) 		polysyndactyly J:70592
Bmp7tm1Rob/Bmp7tm1Rob
Bmpr1btm1Kml/Bmpr1btm1Kml
involves: 129S/SvEv * C57BL/6J 		abnormal humerus morphology J:59282
abnormal scapula morphology J:59282
brachyphalangia J:59282
decreased autopod size J:59282
short humerus J:59282
short metacarpal bones J:59282
short radius J:59282
short ulna J:59282
Bmp7tm6(cre)Rob/Bmp7+
Smad4tm1Rob/Smad4tm1.1Rob
involves: 129S/SvEv * C57BL/6 * SJL 		abnormal kidney development J:108109
abnormal renal glomerulus morphology J:108109
decreased kidney collecting duct number J:108109
hydroureter J:108109
kidney cyst J:108109
perinatal lethality, incomplete penetrance J:108109
postnatal lethality, complete penetrance J:108109
small kidney J:108109
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory