Xpc Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Xpc
xeroderma pigmentosum, complementation group C
MGI:103557

11 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Xpc^tm1Brd/Xpc^tm1Brd involves: 129S7/SvEvBrd * C57BL	abnormal cell physiology	J:28708
	increased incidence of tumors by UV-induction	J:28708
	increased sensitivity to skin irradiation	J:28708
	photosensitivity	J:28708
Xpc^tm1Ecf/Xpc⁺ involves: 129 * SKH1	increased sensitivity to skin irradiation	J:120007
Xpc^tm1Ecf/Xpc^tm1Ecf involves: 129	increased cellular sensitivity to ultraviolet irradiation	J:80212
Xpc^tm1Ecf/Xpc^tm1Ecf involves: 129	oxidative stress	J:70397
Xpc^tm1Ecf/Xpc^tm1Ecf involves: 129 * C57BL/6	increased lung adenocarcinoma incidence	J:101421
	increased lung adenoma incidence	J:101421
	increased lung tumor incidence	J:101421
Xpc^tm1Ecf/Xpc^tm1Ecf involves: 129 * SKH1	abnormal hair follicle morphology	J:120007
	epidermal hyperplasia	J:120007
	increased sensitivity to skin irradiation	J:120007

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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