Kpna2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kpna2
karyopherin subunit alpha 2
MGI:103561

20 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kpna2^em1(IMPC)Mbp/Kpna2⁺ C57BL/6N-Kpna2^em1(IMPC)Mbp/Ucd	abnormal cholesterol homeostasis	J:211773
	abnormal eye morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	decreased locomotor activity	J:211773
	no spontaneous movement	J:211773
	small kidney	J:211773
	small testis	J:211773
Kpna2^em1(IMPC)Mbp/Kpna2^em1(IMPC)Mbp C57BL/6N-Kpna2^em1(IMPC)Mbp/Ucd	female infertility	J:211773
	male infertility	J:211773
	no spontaneous movement	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Kpna2^em1Alfon/Kpna2^em1Alfon involves: C57BL/6 * CBA	abnormal sperm flagellum morphology	J:338393
	abnormal sperm head morphology	J:338393
	abnormal sperm midpiece morphology	J:338393
	asthenozoospermia	J:338393
	decreased body size	J:338393
	decreased sperm progressive motility	J:338393
	male infertility	J:338393
	prenatal lethality, incomplete penetrance	J:338393
	teratozoospermia	J:338393

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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