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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
MGI:103562
22 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Apoetm1Unc/Apoetm1Unc
Hsd11b1tm1Lex/Hsd11b1tm1Lex
B6.129-Hsd11b1tm1Lex Apoetm1Unc 		abnormal bone marrow cell physiology J:199430
abnormal cytokine secretion J:199430
abnormal macrophage derived foam cell morphology J:199430
normal behavior/neurological phenotype J:199430
normal cardiovascular system phenotype J:199430
decreased cholesterol level J:199430
decreased macrophage cell number J:199430
decreased susceptibility to atherosclerosis J:199430
decreased tumor necrosis factor secretion J:199430
normal growth/size/body region phenotype J:199430
hyperlipidemia J:199430
normal immune system phenotype J:199430
H6pdtm1Pmst/H6pdtm1Pmst
Hsd11b1tm1.1Ggla/Hsd11b1tm1.1Ggla
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal skeletal muscle fiber morphology J:189132
centrally nucleated skeletal muscle fibers J:189132
decreased body weight J:189132
decreased circulating glucose level J:189132
decreased lean body mass J:189132
decreased quadriceps weight J:189132
decreased tibialis anterior weight J:189132
enlarged adrenal glands J:189132
increased skeletal muscle glycogen level J:189132
skeletal muscle atrophy J:189132
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory