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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hand2
heart and neural crest derivatives expressed 2
MGI:103580
43 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Ednratm7(Hand2)Hku/Ednra+
chimera involves: 129 * C57BL/6 * ICR
abnormal gonial bone morphology J:224515
abnormal Meckel's cartilage morphology J:224515
abnormal temporal bone squamous part morphology J:224515
absent gonial bone J:224515
absent temporal bone squamous part J:224515
perinatal lethality, complete penetrance J:224515
upper jaw to lower jaw transformation J:224515
Gli3Xt-J/Gli3Xt-J
Hand2tm1.1Zllr/Hand2tm1.2Zllr
Tg(Prrx1-cre)1Cjt/0
involves: 129 * BALB/cJ * C3H/HeJ * C57BL/6 * SJL
abnormal autopod morphology J:159210
abnormal forelimb stylopod morphology J:159210
abnormal forelimb zeugopod morphology J:159210
abnormal limb development J:159210
postaxial polydactyly J:159210
preaxial polydactyly J:159210
Hand1tm2.1(Hand1)Abfi/Hand1tm2.1(Hand1)Abfi
Hand2tm1Dsr/Hand2tm1Dsr
involves: 129S7/SvEvBrd
abnormal cardiovascular system morphology J:164028
abnormal rostral-caudal axis patterning J:164028
decreased embryo size J:164028
thin ventricular wall J:164028
Hand2tm1.2Zllr/Hand2+
Is(In8B2-8B3.1;6C1)1Tshir/0
involves: 129 * C57BL/6 * C57BL/10 * NZB * wild-derived
normal limbs/digits/tail phenotype J:198239
Hand2tm1.2Zllr/Hand2tm1.2Zllr
Is(In8B2-8B3.1;6C1)1Tshir/Is(In8B2-8B3.1;6C1)1Tshir
involves: 129 * C57BL/6 * C57BL/10 * NZB * wild-derived
abnormal cervical vertebrae morphology J:198239
abnormal craniofacial morphology J:198239
normal cardiovascular system phenotype J:198239
clavicle hypoplasia J:198239
normal limbs/digits/tail phenotype J:198239
microcephaly J:198239
Hand2tm1Dsr/Hand2+
Nkx2-5tm1Wehi/Nkx2-5+
involves: C57BL/6
normal mortality/aging J:72600
Hand2tm1Dsr/Hand2tm1Dsr
Nkx2-5tm1Wehi/Nkx2-5tm1Wehi
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
abnormal blood vessel morphology J:72600
abnormal cardiac outflow tract development J:72600
abnormal heart atrium morphology J:72600
abnormal sinus venosus morphology J:72600
absent myocardial trabeculae J:72600
congestive heart failure J:72600
embryonic lethality during organogenesis, complete penetrance J:72600
pericardial effusion J:72600
ventricular hypoplasia J:72600
Hand2tm1Dsr/Hand2tm2.1Dsr
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Isl1tm1(cre)Tmj/Isl1+
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
abnormal heart development J:169213
Hand2tm1Dsr/Hand2tm2.1Dsr
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Tg(Tbx1-cre)#Dsr/0
involves: 129 * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6
abnormal cardiac outflow tract development J:169213
decreased heart right ventricle size J:169213
Rr133tm1Eno/Rr133+
Hand2tm2Eno/Hand2tm2Eno
involves: 129S6/SvEvTac * C57BL/6 * SJL
abnormal mandibular angle morphology J:146638
abnormal secondary palate development J:146638
absent suckling reflex J:146638
cleft secondary palate J:146638
decreased tympanic ring size J:146638
failure of palatal shelf elevation J:146638
mandible hypoplasia J:146638
neonatal lethality, complete penetrance J:146638

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory