Ercc5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ercc5
excision repair cross-complementing rodent repair deficiency, complementation group 5
MGI:103582

21 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ercc5^tm1Shm/Ercc5^tm1Shm involves: 129S2/SvPas * C57BL/6J	abnormal digestion	J:53756
	abnormal hepatocyte morphology	J:53756
	abnormal intestine morphology	J:53756
	abnormal small intestine morphology	J:53756
	decreased spleen weight	J:53756
	delayed intestine development	J:53756
	phototoxicity	J:53756
	postnatal growth retardation	J:53756
	small liver	J:53756
	small stomach	J:53756
Ercc5^tm1Shm/Ercc5^tm1Shm Not Specified	abnormal small intestine morphology	J:89911
	phototoxicity	J:89911
	postnatal growth retardation	J:89911
	postnatal lethality, complete penetrance	J:89911
Ercc5^{tm2b(EUCOMM)Hmgu}/Ercc5⁺ C57BL/6N-Ercc5^{tm2b(EUCOMM)Hmgu}/Bay	decreased erythrocyte cell number	J:211773
	decreased hematocrit	J:211773
	increased fasting circulating glucose level	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular hemoglobin concentration	J:211773
	thrombocytosis	J:211773
Ercc5^{tm2b(EUCOMM)Hmgu}/Ercc5^{tm2b(EUCOMM)Hmgu} C57BL/6N-Ercc5^{tm2b(EUCOMM)Hmgu}/Bay	preweaning lethality, complete penetrance	J:211773
Ercc5^tm2Shm/Ercc5^tm2Shm involves: 129S2/SvPas * C57BL/6J	normal growth/size/body region phenotype	J:89911
	normal mortality/aging	J:89911
	phototoxicity	J:89911
Ercc5^tm3Shm/Ercc5^tm3Shm involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal small intestine morphology	J:89911
	phototoxicity	J:89911
	postnatal growth retardation	J:89911
	premature death	J:89911
Ercc5^tm4Shm/Ercc5^tm4Shm involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	normal growth/size/body region phenotype	J:89911
	normal mortality/aging	J:89911
	phototoxicity	J:89911

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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