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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nog
noggin
MGI:104327
57 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Bmp4tm2Blh/Bmp4+
Nogtm1Amc/Nog+
involves: 129S1/Sv * 129S6/SvEvTac 		no abnormal phenotype detected J:110617
Bmp4tm2Blh/Bmp4+
Nogtm1Amc/Nogtm1Amc
involves: 129S1/Sv * 129S6/SvEvTac 		abnormal vertebrae development J:110617
abnormal vertebral arch morphology J:110617
normal nervous system phenotype J:110617
Bmp7tm1Kry/Bmp7tm1Kry
Nogtm1Amc/Nogtm1Amc
either: (involves: 129S1/Sv * C57BL/6) or (involves: 129S1/Sv * CD-1 * ICR) 		normal digestive/alimentary phenotype J:118341
normal nervous system phenotype J:118341
prenatal lethality, complete penetrance J:118341
Cer1tm1Belo/Cer1tm1Belo
Nogtm1Amc/Nogtm1Amc
involves: 129S1/Sv * 129X1/SvJ 		abnormal basicranium morphology J:74136
abnormal frontal bone morphology J:74136
abnormal interparietal bone morphology J:74136
abnormal neural tube closure J:74136
abnormal occipital bone morphology J:74136
abnormal parietal bone morphology J:74136
absent tail J:74136
exencephaly J:74136
open neural tube J:74136
prenatal lethality J:74136
short limbs J:74136
Chrdtm1Emdr/Chrdtm1Emdr
Nogtm1Amc/Nogtm1Amc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J 		abnormal cephalic neural fold morphology J:60303
abnormal diencephalon morphology J:60303
abnormal direction of heart looping J:60303
abnormal facial morphology J:60303
abnormal forebrain development J:60303
abnormal left-right axis patterning J:60303
abnormal mesendoderm development J:60303
abnormal telencephalon morphology J:60303
absent mandible J:60303
absent nasal placodes J:60303
absent notochord J:60303
absent sclerotome J:60303
anophthalmia J:60303
aprosencephaly J:60303
cyclopia J:60303
decreased forebrain size J:60303
embryonic lethality between somite formation and embryo turning, incomplete penetrance J:60303
embryonic lethality during organogenesis, incomplete penetrance J:60303
holoprosencephaly J:60303
lethality throughout fetal growth and development, complete penetrance J:60303
proboscis J:60303
small pharynx J:60303
tracheoesophageal fistula J:60303
Chrdtm1Emdr/Chrdtm1Emdr
Nogtm1Amc/Nogtm1Amc
involves: 129S1/Sv * 129X1/SvJ * ICR 		abnormal direction of heart looping J:137629
Grem1tm1Ecan/Grem1+
Nogtm1.1Rmh/Nogtm1.1Rmh
Tmem163Tg(ACTB-cre)2Mrt/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL 		abnormal neural tube morphology J:169133
decreased somite size J:169133
open neural tube J:169133
Grem1tm1Ecan/Grem1tm1Ecan
Nogtm1.1Rmh/Nogtm1.1Rmh
Tmem163Tg(ACTB-cre)2Mrt/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL 		abnormal brain development J:169133
abnormal head development J:169133
abnormal somite development J:169133
abnormal tail development J:169133
absent sclerotome J:169133
decreased somite size J:169133
kinked neural tube J:169133
open neural tube J:169133
Nbl1tm1Rmh/Nbl1tm1Rmh
Nogtm1Amc/Nogtm1Amc
involves: 129P2/OlaHsd * 129S1/Sv * 129S6/SvEvTac 		lumbar vertebral transformation J:67351
Nodaltm1Rob/Nodal+
Nogtm1Amc/Nogtm1Amc
involves: 129S/SvEv * 129S1/Sv 		normal embryo phenotype J:161524
Nogtm1Amc/Nog+
Smad3tm1Xfw/Smad3+
involves: 129/Sv * 129S1/Sv 		abnormal embryonic tissue morphology J:161524
Nogtm1Amc/Nog+
Smad3tm1Xfw/Smad3tm1Xfw
involves: 129/Sv * 129S1/Sv 		abnormal embryonic tissue morphology J:161524
holoprosencephaly J:161524
Nogtm1Amc/Nogtm1Amc
Smad3tm1Xfw/Smad3+
involves: 129/Sv * 129S1/Sv 		abnormal anterior definitive endoderm morphology J:161524
abnormal embryonic tissue morphology J:161524
abnormal mesendoderm development J:161524
abnormal prechordal plate morphology J:161524
abnormal primitive streak formation J:161524
holoprosencephaly J:161524
Nogtm1Amc/Nogtm1Amc
Smad3tm1Xfw/Smad3tm1Xfw
involves: 129/Sv * 129S1/Sv 		abnormal embryonic tissue morphology J:161524
holoprosencephaly J:161524
Tg(Krt14-Bmp4)#Jake/0
Tg(Krt14-Nog)#Jake/0
involves: BALB/c * C57BL/6 * FVB 		abnormal enamel morphology J:156471
abnormal upper incisor morphology J:156471
interdigital webbing J:78767
normal limbs/digits/tail phenotype J:78767
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory