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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mitf
melanogenesis associated transcription factor
MGI:104554
34 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
In(6)1J/In(6)1J
Mitfem1Chuan/Mitfem1Chuan
B6N.C3H-In(6)1J Mitfem1Chuan/Chuan 		decreased eye pigmentation J:330636
white spotting J:330636
In(6)1J/In(6)1J
Mitfem1Chuan/Mitfem1Chuan
Tprkbem1Chuan/Tprkbem1Chuan
B6N.Cg-In(6)1J Tprkbem1Chuan Mitfem1Chuan 		normal mortality/aging J:330636
Mitfem1Chuan/Mitfem1Chuan
Tprkbem1Chuan/Tprkbem1Chuan
B6N.Cg-Tprkbem1Chuan Mitfem1Chuan 		embryonic lethality, complete penetrance J:330636
Mitfmi-ew/Mitfmi-ew
Tfe3tm1Est/Tfe3+
either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW) 		absent coat pigmentation J:89821
microphthalmia J:89821
osteopetrosis J:89821
Mitfmi-ew/Mitfmi-ew
Tfe3tm1Est/Tfe3tm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW) 		abnormal osteoclast morphology J:89821
absent coat pigmentation J:89821
decreased body weight J:89821
delayed tooth eruption J:89821
microphthalmia J:89821
osteopetrosis J:89821
postnatal lethality, complete penetrance J:89821
Mitfmi-rw/Mitfmi-rw
Tg(Tyr-Tfec)#Bhar/?
involves: C57BL/6 * CBA 		normal vision/eye phenotype J:188155
Mitfmi-vga9/Mitf+
Pax6Sey-Neu/Pax6+
involves: C57BL/6 * CBA 		abnormal retina pigment epithelium morphology J:188155
Mitfmi-vga9/Mitfmi-vga9
Pax6Sey-Neu/Pax6+
involves: C57BL/6 * CBA 		abnormal retina pigment epithelium morphology J:188155
Mitfmi-vga9/Mitfmi-vga9
Pax6Sey-Neu/Pax6Sey-Neu
involves: C57BL/6 * CBA 		abnormal retina pigment epithelium morphology J:188155
Mitfmi-vga9/Mitfmi-vga9
Tfe3tm1Est/Tfe3tm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL/6 * CBA) or (involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA) 		abnormal osteoclast morphology J:89821
absent coat pigmentation J:89821
delayed tooth eruption J:89821
microphthalmia J:89821
osteopetrosis J:89821
postnatal lethality, complete penetrance J:89821
Mitfmi-vga9/Mitfmi-vga9
Tg(PAX6)77Ndha/Tg(PAX6)77Ndha
involves: C57BL/6 * CBA 		normal vision/eye phenotype J:188155
Mitfmi-vit/Mitfmi-vit
Tg(KRT14-Edn3)1Takk/?
involves: C57BL/6 * C57BL/6J * DBA/2 		abnormal coat/hair pigmentation J:100658
abnormal melanocyte morphology J:100658
white spotting J:100658
MitfMi-wh/Mitf+
Myo5ad/Myo5ad
involves: C57BL * DBA 		decreased eye pigmentation J:13058
diluted coat color J:13058
MitfMi-wh/MitfMi-wh
Tfe3tm1Est/Tfe3tm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA) 		absent coat pigmentation J:89821
decreased body weight J:89821
microphthalmia J:89821
osteopetrosis J:89821
postnatal lethality, incomplete penetrance J:89821
MitfMi-wh/MitfMi-wh
Tfe3tm1Est/Tfe3tm1Est
Tfectm1Est/Tfectm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA) 		absent coat pigmentation J:89821
microphthalmia J:89821
osteopetrosis J:89821
MitfMi-wh/MitfMi-wh
Tfebtm1Est/Tfeb+
involves: 129S1/Sv * C57BL * C57BL/6J * DBA 		absent coat pigmentation J:89821
microphthalmia J:89821
normal skeleton phenotype J:89821
MitfMi-wh/MitfMi-wh
Tfectm1Est/Tfectm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA) 		absent coat pigmentation J:89821
microphthalmia J:89821
normal skeleton phenotype J:89821
MitfMi/Mitf+
Vsx2or-J/Vsx2or-J
involves: 129S1/Sv * 129X1/SvJ 		abnormal eye morphology J:190452
abnormal eye size J:190452
MitfMi/Mitf+
Vsx2tm1.1Itl/Vsx2tm1.1Itl
involves: 129S1/Sv * 129S6/SvEvTac 		abnormal eye morphology J:190452
abnormal eye size J:190452
MitfMi/Mitf+
Vsx2tm1.1Eml/Vsx2tm1.1Eml
involves: 129S1/Sv * 129X1/SvJ 		abnormal eye morphology J:190452
abnormal eye size J:190452
MitfMi/MitfMi
Tfe3tm1Est/Tfe3tm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J) 		abnormal osteoclast morphology J:89821
absent coat pigmentation J:89821
microphthalmia J:89821
osteopetrosis J:89821
MitfMi/MitfMi
Tfectm1Est/Tfectm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J) 		absent coat pigmentation J:89821
microphthalmia J:89821
osteopetrosis J:89821
MitfTg(Tff3-Tmem207)2Tamo/Mitf+
involves: C57BL/6 		abnormal kidney pelvis morphology J:244533
abnormal loop of Henle morphology J:244533
dilated renal tubule J:244533
increased glomerular capsule space J:244533
kidney inflammation J:244533
liver cyst J:244533
pancreas cyst J:244533
polycystic kidney J:244533
renal interstitial fibrosis J:244533
renal tubule atrophy J:244533
MitfTg(Tff3-Tmem207)2Tamo/MitfTg(Tff3-Tmem207)2Tamo
involves: C57BL/6 		increased circulating creatinine level J:244533
liver cyst J:244533
pancreas cyst J:244533
polycystic kidney J:244533
Mitftm1.2Arnh/Mitftm1.2Arnh
involves: 129S1/Sv * C3H/HeJ * C57BL/6 		phenotypic reversion J:130168
Mitftm3.1Arnh/Mitftm3.1Arnh
Pax6Sey-Neu/Pax6+
involves: 129S6/SvEvTac * C57BL/6N 		abnormal retina pigment epithelium morphology J:188155
Mitftm3.1Arnh/Mitftm3.1Arnh
Tg(PAX6)77Ndha/?
involves: 129S6/SvEvTac * C57BL/6N * CBA 		normal vision/eye phenotype J:188155
Mitftm5.1Arnh/Mitftm5.1Arnh
Kittm1Alf/Kit+
involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N 		abnormal coat/hair pigmentation J:182722
abnormal hair follicle melanocyte morphology J:182722
abnormal melanocyte morphology J:182722
belly spot J:182722
Mitftm7.1Arnh/Mitftm7.1Arnh
Kittm1Alf/Kit+
involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N 		belly spot J:182722
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory