About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mitf
melanogenesis associated transcription factor
MGI:104554
34 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
In(6)1J/In(6)1J
Mitfem1Chuan/Mitfem1Chuan
B6N.C3H-In(6)1J Mitfem1Chuan/Chuan 		decreased eye pigmentation J:330636
white spotting J:330636
In(6)1J/In(6)1J
Mitfem1Chuan/Mitfem1Chuan
Tprkbem1Chuan/Tprkbem1Chuan
B6N.Cg-In(6)1J Tprkbem1Chuan Mitfem1Chuan 		normal mortality/aging J:330636
Mitfem1Chuan/Mitfem1Chuan
Tprkbem1Chuan/Tprkbem1Chuan
B6N.Cg-Tprkbem1Chuan Mitfem1Chuan 		embryonic lethality, complete penetrance J:330636
Mitfmi-ew/Mitfmi-ew
Tfe3tm1Est/Tfe3+
either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW) 		absent coat pigmentation J:89821
microphthalmia J:89821
osteopetrosis J:89821
Mitfmi-ew/Mitfmi-ew
Tfe3tm1Est/Tfe3tm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW) 		abnormal osteoclast morphology J:89821
absent coat pigmentation J:89821
decreased body weight J:89821
delayed tooth eruption J:89821
microphthalmia J:89821
osteopetrosis J:89821
postnatal lethality, complete penetrance J:89821
Mitfmi-rw/Mitfmi-rw
Tg(Tyr-Tfec)#Bhar/?
involves: C57BL/6 * CBA 		normal vision/eye phenotype J:188155
Mitfmi-vga9/Mitf+
Pax6Sey-Neu/Pax6+
involves: C57BL/6 * CBA 		abnormal retina pigment epithelium morphology J:188155
Mitfmi-vga9/Mitfmi-vga9
Pax6Sey-Neu/Pax6+
involves: C57BL/6 * CBA 		abnormal retina pigment epithelium morphology J:188155
Mitfmi-vga9/Mitfmi-vga9
Pax6Sey-Neu/Pax6Sey-Neu
involves: C57BL/6 * CBA 		abnormal retina pigment epithelium morphology J:188155
Mitfmi-vga9/Mitfmi-vga9
Tfe3tm1Est/Tfe3tm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL/6 * CBA) or (involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA) 		abnormal osteoclast morphology J:89821
absent coat pigmentation J:89821
delayed tooth eruption J:89821
microphthalmia J:89821
osteopetrosis J:89821
postnatal lethality, complete penetrance J:89821
Mitfmi-vga9/Mitfmi-vga9
Tg(PAX6)77Ndha/Tg(PAX6)77Ndha
involves: C57BL/6 * CBA 		normal vision/eye phenotype J:188155
Mitfmi-vit/Mitfmi-vit
Tg(KRT14-Edn3)1Takk/?
involves: C57BL/6 * C57BL/6J * DBA/2 		abnormal coat/hair pigmentation J:100658
abnormal melanocyte morphology J:100658
white spotting J:100658
MitfMi-wh/Mitf+
Myo5ad/Myo5ad
involves: C57BL * DBA 		decreased eye pigmentation J:13058
diluted coat color J:13058
MitfMi-wh/MitfMi-wh
Tfe3tm1Est/Tfe3tm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA) 		absent coat pigmentation J:89821
decreased body weight J:89821
microphthalmia J:89821
osteopetrosis J:89821
postnatal lethality, incomplete penetrance J:89821
MitfMi-wh/MitfMi-wh
Tfe3tm1Est/Tfe3tm1Est
Tfectm1Est/Tfectm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA) 		absent coat pigmentation J:89821
microphthalmia J:89821
osteopetrosis J:89821
MitfMi-wh/MitfMi-wh
Tfebtm1Est/Tfeb+
involves: 129S1/Sv * C57BL * C57BL/6J * DBA 		absent coat pigmentation J:89821
microphthalmia J:89821
normal skeleton phenotype J:89821
MitfMi-wh/MitfMi-wh
Tfectm1Est/Tfectm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA) 		absent coat pigmentation J:89821
microphthalmia J:89821
normal skeleton phenotype J:89821
MitfMi/Mitf+
Vsx2or-J/Vsx2or-J
involves: 129S1/Sv * 129X1/SvJ 		abnormal eye morphology J:190452
abnormal eye size J:190452
MitfMi/Mitf+
Vsx2tm1.1Itl/Vsx2tm1.1Itl
involves: 129S1/Sv * 129S6/SvEvTac 		abnormal eye morphology J:190452
abnormal eye size J:190452
MitfMi/Mitf+
Vsx2tm1.1Eml/Vsx2tm1.1Eml
involves: 129S1/Sv * 129X1/SvJ 		abnormal eye morphology J:190452
abnormal eye size J:190452
MitfMi/MitfMi
Tfe3tm1Est/Tfe3tm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J) 		abnormal osteoclast morphology J:89821
absent coat pigmentation J:89821
microphthalmia J:89821
osteopetrosis J:89821
MitfMi/MitfMi
Tfectm1Est/Tfectm1Est
either: (involves: 129/Sv * 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J) 		absent coat pigmentation J:89821
microphthalmia J:89821
osteopetrosis J:89821
MitfTg(Tff3-Tmem207)2Tamo/Mitf+
involves: C57BL/6 		abnormal kidney pelvis morphology J:244533
abnormal loop of Henle morphology J:244533
dilated renal tubule J:244533
increased glomerular capsule space J:244533
kidney inflammation J:244533
liver cyst J:244533
pancreas cyst J:244533
polycystic kidney J:244533
renal interstitial fibrosis J:244533
renal tubule atrophy J:244533
MitfTg(Tff3-Tmem207)2Tamo/MitfTg(Tff3-Tmem207)2Tamo
involves: C57BL/6 		increased circulating creatinine level J:244533
liver cyst J:244533
pancreas cyst J:244533
polycystic kidney J:244533
Mitftm1.2Arnh/Mitftm1.2Arnh
involves: 129S1/Sv * C3H/HeJ * C57BL/6 		phenotypic reversion J:130168
Mitftm3.1Arnh/Mitftm3.1Arnh
Pax6Sey-Neu/Pax6+
involves: 129S6/SvEvTac * C57BL/6N 		abnormal retina pigment epithelium morphology J:188155
Mitftm3.1Arnh/Mitftm3.1Arnh
Tg(PAX6)77Ndha/?
involves: 129S6/SvEvTac * C57BL/6N * CBA 		normal vision/eye phenotype J:188155
Mitftm5.1Arnh/Mitftm5.1Arnh
Kittm1Alf/Kit+
involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N 		abnormal coat/hair pigmentation J:182722
abnormal hair follicle melanocyte morphology J:182722
abnormal melanocyte morphology J:182722
belly spot J:182722
Mitftm7.1Arnh/Mitftm7.1Arnh
Kittm1Alf/Kit+
involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N 		belly spot J:182722
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory