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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rps6ka3
ribosomal protein S6 kinase polypeptide 3
MGI:104557
59 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Rps6ka3tm1.1Kry/Rps6ka3+
involves: 129X1/SvJ 		abnormal bone mineralization J:89403
abnormal bone ossification J:89403
abnormal osteoblast physiology J:89403
normal cardiovascular system phenotype J:89403
decreased bone mass J:89403
decreased bone mineral density J:89403
decreased length of long bones J:89403
normal digestive/alimentary phenotype J:89403
normal endocrine/exocrine gland phenotype J:89403
normal hearing/vestibular/ear phenotype J:89403
normal hematopoietic system phenotype J:89403
normal immune system phenotype J:89403
normal integument phenotype J:89403
large fontanelles J:89403
normal liver/biliary system phenotype J:89403
normal muscle phenotype J:89403
normal nervous system phenotype J:89403
normal renal/urinary system phenotype J:89403
normal reproductive system phenotype J:89403
normal respiratory system phenotype J:89403
small frontal bone J:89403
small interparietal bone J:89403
small parietal bone J:89403
small vertebrae J:89403
normal taste/olfaction phenotype J:89403
normal vision/eye phenotype J:89403
wide cranial sutures J:89403
Rps6ka3tm1.1Kry/Y
involves: 129X1/SvJ 		abnormal bone mineralization J:89403
abnormal bone ossification J:89403
abnormal diastema morphology J:211945
abnormal long bone morphology J:89403
abnormal molar crown morphology J:211945
abnormal molar morphology J:211945
abnormal tooth morphology J:211945
abnormal tooth root development J:211945
decreased bone mass J:89403
decreased bone trabecula number J:89403
decreased cranium length J:211945
decreased length of long bones J:89403
large fontanelles J:89403
short frontal bone J:211945
small frontal bone J:89403
small interparietal bone J:89403
small parietal bone J:89403
small vertebrae J:89403
supernumerary teeth J:211945
wide cranial sutures J:89403
Rps6ka3tm1.1Kry/Rps6ka3tm1.1Kry
B6.129X1(Cg)-Rps6ka3tm1.1Kry 		abnormal associative learning J:201540
abnormal CNS synaptic transmission J:201540
abnormal contextual conditioning behavior J:201540
abnormal dendritic spine morphology J:201540
abnormal excitatory postsynaptic potential J:201540
abnormal postsynaptic density morphology J:201540
abnormal synapse morphology J:201540
reduced AMPA-mediated synaptic currents J:201540
short excitatory postsynaptic current decay time J:201540
Rps6ka3tm1.1Kry/Rps6ka3tm1.1Kry
involves: 129X1/SvJ 		abnormal bone mineralization J:89403
abnormal bone ossification J:89403
abnormal osteoblast physiology J:89403
normal cardiovascular system phenotype J:89403
decreased bone mass J:89403
decreased bone mineral density J:89403
decreased bone trabecula number J:89403
decreased length of long bones J:89403
normal digestive/alimentary phenotype J:89403
normal endocrine/exocrine gland phenotype J:89403
normal hearing/vestibular/ear phenotype J:89403
normal hematopoietic system phenotype J:89403
normal immune system phenotype J:89403
normal integument phenotype J:89403
large fontanelles J:89403
normal liver/biliary system phenotype J:89403
normal muscle phenotype J:89403
normal nervous system phenotype J:89403
normal renal/urinary system phenotype J:89403
normal reproductive system phenotype J:89403
normal respiratory system phenotype J:89403
small frontal bone J:89403
small interparietal bone J:89403
small parietal bone J:89403
small vertebrae J:89403
normal taste/olfaction phenotype J:89403
normal vision/eye phenotype J:89403
wide cranial sutures J:89403
Rps6ka3tm1Ljg/Y
involves: 129 * C57BL/6 		abnormal learning/memory/conditioning J:67575
decreased body length J:67575
decreased body size J:67575
decreased body weight J:83536
decreased circulating leptin level J:83536
decreased skeletal muscle glycogen level J:67575
decreased white adipose tissue amount J:83536
impaired coordination J:67575
impaired glucose tolerance J:83536
increased circulating glucose level J:83536
increased circulating insulin level J:83536
infertility J:83536
insulin resistance J:83536
Rps6ka3tm1Ljg/Rps6ka3tm1Ljg
involves: 129 * C57BL/6 		infertility J:83536
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory