Hcls1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hcls1
hematopoietic cell specific Lyn substrate 1
MGI:104568

13 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hcls1^{em1(IMPC)Ccpcz}/Hcls1^{em1(IMPC)Ccpcz} C57BL/6NCrl-Hcls1^{em1(IMPC)Ccpcz}/Ccpcz	abnormal eye morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal thymus morphology	J:211773
	absent optic nerve	J:211773
	enlarged spleen	J:211773
	enlarged thymus	J:211773
	increased kidney weight	J:211773
	small testis	J:211773
Hcls1^tm1Wtn/Hcls1^tm1Wtn involves: 129P2/OlaHsd * C57BL/6	abnormal B cell physiology	J:28146
	abnormal humoral immune response	J:28146
	decreased B cell number	J:28146
	decreased T cell proliferation	J:28146
Hcls1^tm2Wtn/Hcls1^tm2Wtn involves: 129P2/OlaHsd * C57BL/6	abnormal B cell physiology	J:28146
	abnormal humoral immune response	J:28146
	decreased B cell number	J:28146
	decreased T cell proliferation	J:28146

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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