Rapgef1 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rapgef1
Rap guanine nucleotide exchange factor (GEF) 1
MGI:104580

13 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rapgef1^{Gt(pGT1.8geo)5Pgr}/Rapgef1^{Gt(pGT1.8geo)5Pgr} involves: 129	abnormal embryonic neuroepithelium morphology	J:119299
Rapgef1^{Gt(pGT1.8geo)5Pgr}/Rapgef1^{Gt(pGT1.8geo)5Pgr} involves: 129/Sv * C57BL/6 * Swiss	abnormal brain vasculature morphology	J:80219
	abnormal cell adhesion	J:80219
	abnormal nervous system morphology	J:80219
	abnormal vascular smooth muscle morphology	J:80219
	decreased fibroblast cell migration	J:80219
	edema	J:80219
	embryonic lethality during organogenesis, complete penetrance	J:80219
	hemorrhage	J:80219
	vascular smooth muscle hypoplasia	J:80219
Rapgef1^{tm1b(KOMP)Wtsi}/Rapgef1⁺ C57BL/6N-Rapgef1^{tm1b(KOMP)Wtsi}/J	abnormal retina morphology	J:211773
Rapgef1^{tm1b(KOMP)Wtsi}/Rapgef1^{tm1b(KOMP)Wtsi} C57BL/6N-Rapgef1^{tm1b(KOMP)Wtsi}/J	preweaning lethality, complete penetrance	J:211773
Rapgef1^tm1Mats/Rapgef1^tm1Mats involves: 129P2/OlaHsd * C57BL/6J	embryonic lethality between implantation and somite formation, complete penetrance	J:77323

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24