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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Eps15
epidermal growth factor receptor pathway substrate 15
MGI:104583
25 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Eps15tm1c(KOMP)Wtsi/Eps15tm1c(KOMP)Wtsi
Eps15l1tm1.1Noff/Eps15l1tm1.1Noff
Tg(Tek-cre)1Ywa/0
involves: C57BL/6 * C57BL/6N * SJL 		abnormal vascular development J:272122
anisocytosis J:272122
decreased mean corpuscular volume J:272122
increased red blood cell distribution width J:272122
reticulocytosis J:272122
Eps15tm1c(KOMP)Wtsi/Eps15tm1c(KOMP)Wtsi
Eps15l1tm2.1Noff/Eps15l1tm2.1Noff
Tg(Tek-cre)1Ywa/0
involves: C57BL/6 * C57BL/6N * SJL 		abnormal endocytosis J:272122
abnormal erythropoiesis J:272122
anemia J:272122
anisopoikilocytosis J:272122
decreased erythrocyte cell number J:272122
decreased hematocrit J:272122
decreased hemoglobin content J:272122
decreased mean corpuscular volume J:272122
extramedullary hematopoiesis J:272122
hypochromic microcytic anemia J:272122
increased circulating iron level J:272122
reticulocytosis J:272122
Eps15tm1Noff/Eps15tm1Noff
Eps15l1tm1.1Noff/Eps15l1tm1.1Noff
involves: 129 * C57BL/6 		abnormal embryo morphology J:272122
abnormal midbrain-hindbrain boundary morphology J:272122
abnormal vasculogenesis J:272122
abnormal vitelline vasculature morphology J:272122
absent limb buds J:272122
delayed heart looping J:272122
embryonic growth retardation J:272122
embryonic lethality during organogenesis, complete penetrance J:272122
fused somites J:272122
pallor J:272122
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory