About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ccr1
C-C motif chemokine receptor 1
MGI:104618
45 phenotypes from 2 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Ccr1tm1Cge/Ccr1tm1Cge
C.129S4-Ccr1tm1Cge 		decreased airway responsiveness J:95242
decreased CD4-positive, alpha-beta T cell number J:95242
decreased CD8-positive, alpha-beta T cell number J:95242
decreased interleukin-13 secretion J:95242
decreased susceptibility to Riboviria infection J:95242
Ccr1tm1Cge/Ccr1tm1Cge
involves: 129S4/SvJae 		abnormal renal glomerulus morphology J:115119
decreased tumor necrosis factor secretion J:43569
glomerular crescent J:115119
glomerulonephritis J:115119
glomerulosclerosis J:115119
normal immune system phenotype J:115119
impaired neutrophil recruitment J:43569
increased blood urea nitrogen level J:115119
increased IgG2a level J:115119
increased interferon-gamma secretion J:115119
increased susceptibility to type IV hypersensitivity reaction J:115119
increased tumor necrosis factor secretion J:115119
increased urine protein level J:115119
lung inflammation J:43569
Ccr1tm1Cge/Ccr1tm1Cge
involves: 129S4/SvJae * BALB/c 		abnormal chemokine secretion J:169909
abnormal circulating chemokine level J:169909
abnormal macrophage physiology J:169909
decreased circulating interferon-gamma level J:169909
decreased interleukin-10 secretion J:169909
decreased susceptibility to bacterial infection J:169909
decreased susceptibility to bacterial infection induced morbidity/mortality J:169909
decreased tumor necrosis factor secretion J:169909
increased interleukin-12 secretion J:169909
increased macrophage nitric oxide production J:169909
increased tumor necrosis factor secretion J:169909
Ccr1tm1Cge/Ccr1tm1Cge
involves: 129S4/SvJae * C57BL/6 		cecum inflammation J:107677
decreased susceptibility to bacterial infection J:107677
decreased susceptibility to experimental autoimmune encephalomyelitis J:63952
normal immune system phenotype J:63952
increased length of allograft survival J:59235
Ccr1tm1Gao/Ccr1tm1Gao
B6.129S4-Ccr1tm1Gao 		abnormal cellular extravasation J:104744
abnormal leukocyte adhesion J:104744
abnormal response to cardiac infarction J:104744
bronchiolitis J:162707
increased susceptibility to Coronaviridae infection J:162707
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:162707
Ccr1tm1Gao/Ccr1tm1Gao
involves: 129S4/SvJae 		abnormal Kupffer cell morphology J:152548
Ccr1tm1Gao/Ccr1tm1Gao
involves: 129S4/SvJae * C57BL/6 		abnormal neutrophil physiology J:41324
granulomatous inflammation J:41324
normal immune system phenotype J:41324
impaired hematopoiesis J:41324
increased susceptibility to fungal infection J:41324
increased susceptibility to parasitic infection J:41324
Ccr1tm1Gao/Ccr1tm1Gao
involves: C57BL/6 		decreased mast cell number J:94599
decreased susceptibility to type III hypersensitivity reaction J:94599
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory