Alx1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Alx1
ALX homeobox 1
MGI:104621

37 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Alx1^em1Jian/Alx1^em1Jian Alx4^Lst-2J/Alx4⁺ involves: C57BL/6J * C57BL/6N * CD-1	abnormal lateral nasal prominence morphology	J:320497
	abnormal premaxilla morphology	J:320497
	abnormal presphenoid bone morphology	J:320497
	broad nasal bridge	J:320497
	depressed nasal bridge	J:320497
	midline cleft upper lip	J:320497
	short philtrum	J:320497
Alx1^em1Jian/Alx1^em1Jian Alx4^Lst-2J/Alx4^Lst-2J involves: C57BL/6J * C57BL/6N * CD-1	abnormal lateral nasal prominence morphology	J:320497
	abnormal medial nasal prominence morphology	J:320497
	abnormal premaxilla morphology	J:320497
	midline cleft upper lip	J:320497
	midline facial cleft	J:320497
Alx1^em1Jian/Alx1^em1Jian Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}/Gt(ROSA)26Sor⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N * CBA/J	normal embryo phenotype	J:320497
Alx1^tm1Crm/Alx1⁺ Alx4^tm1Rwi/Alx4⁺ involves: 129S6/SvEvTac * 129S7/SvEvBrd	no abnormal phenotype detected	J:51128
Alx1^tm1Crm/Alx1⁺ Alx4^tm1Rwi/Alx4^tm1Rwi involves: 129S6/SvEvTac * 129S7/SvEvBrd	abnormal basisphenoid bone morphology	J:51128
	abnormal nasal septum cartilage morphology	J:51128
	abnormal neurocranium morphology	J:51128
	cleft palate	J:51128
	eyelids open at birth	J:51128
	herniated abdominal wall	J:51128
	midline facial cleft	J:51128
	polydactyly	J:51128
	short mandible	J:51128
	short tibia	J:51128
	small frontal bone	J:51128
	small mandible	J:51128
	small occipital bone	J:51128
	small parietal bone	J:51128
	small temporal bone	J:51128
Alx1^tm1Crm/Alx1^tm1Crm Alx3^tm1Hubr/Alx3^tm1Hubr involves: 129P2/OlaHsd * 129S7/SvEvBrd	abnormal scapula morphology	J:101708
Alx1^tm1Crm/Alx1^tm1Crm Alx4^lst-J/Alx4^lst-J involves: 129S7/SvEvBrd * C3HeB/FeJ * C57BL/6J	abnormal clavicle morphology	J:101708
	abnormal scapula morphology	J:101708
	abnormal scapular spine morphology	J:101708
	small acromion	J:101708
	small pubis	J:101708
Alx1^tm1Crm/Alx1^tm1Crm Alx4^lst-J/Alx4^lst-J Tbx15^de-H/Tbx15⁺ involves: 129S7/SvEvBrd * C3H * C57BL/6J	abnormal scapula morphology	J:101708
	abnormal scapular spine morphology	J:101708
Alx1^tm1Crm/Alx1^tm1Crm Alx4^lst-J/Alx4^lst-J Tbx15^de-H/Tbx15^de-H involves: 129S7/SvEvBrd * C3H * C57BL/6J	absent clavicle	J:101708
	small scapula	J:101708
Alx1^tm1Crm/Alx1^tm1Crm Alx4^tm1Rwi/Alx4⁺ involves: 129S6/SvEvTac * 129S7/SvEvBrd	abnormal basisphenoid bone morphology	J:51128
	abnormal nasal septum cartilage morphology	J:51128
	exencephaly	J:51128
	midline facial cleft	J:51128
	short mandible	J:51128
Alx1^tm1Crm/Alx1^tm1Crm Alx4^tm1Rwi/Alx4^tm1Rwi involves: 129S6/SvEvTac * 129S7/SvEvBrd	asymmetric rib joints	J:51128
	decreased rib number	J:51128
	exencephaly	J:51128
	herniated abdominal wall	J:51128
	midline facial cleft	J:51128
	polydactyly	J:51128
	short tibia	J:51128
	split sternum	J:51128
Alx1^tm1Crm/Alx1^tm1Crm Tbx15^de-H/Tbx15^de-H involves: 129S7/SvEvBrd * C3H * C57BL/6JEi	scapular bone foramen	J:101708

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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