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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tle3
transducin-like enhancer of split 3
MGI:104634
32 phenotypes from 4 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tle3em1(IMPC)Mbp/Tle3em1(IMPC)Mbp
C57BL/6N-Tle3em1(IMPC)Mbp/MbpMmucd 		abnormal brain morphology J:211773
abnormal spleen morphology J:211773
abnormal testis morphology J:211773
abnormal vitreous body morphology J:211773
cataract J:211773
decreased brain size J:211773
persistence of hyaloid vascular system J:211773
small spleen J:211773
small testis J:211773
Tle3Gt(XP0165)Wtsi/Tle3Gt(XP0165)Wtsi
involves: 129P2/OlaHsd 		abnormal adipose tissue development J:172245
abnormal cell differentiation J:172245
embryonic lethality, complete penetrance J:172245
Tle3tm1.1Pton/Tle3tm1.1Pton
Tg(Adipoq-cre)1Evdr/0
involves: 129P2/OlaHsd * C57BL/6J * FVB/NJ 		abnormal brown adipose tissue morphology J:198134
abnormal brown fat cell morphology J:198134
abnormal inguinal fat pad morphology J:198134
normal behavior/neurological phenotype J:198134
decreased susceptibility to induced hypothermia J:198134
increased core body temperature J:198134
increased energy expenditure J:198134
Tle3tm1Jcc/Tle3tm1Jcc
involves: 129P2/OlaHsd 		abnormal pancreas development J:183486
abnormal pancreatic alpha cell differentiation J:183486
abnormal pancreatic alpha cell morphology J:183486
abnormal pancreatic beta cell differentiation J:183486
abnormal pancreatic beta cell morphology J:183486
abnormal pancreatic delta cell differentiation J:183486
abnormal pancreatic epsilon cell differentiation J:183486
abnormal pancreatic epsilon cell morphology J:183486
abnormal placenta morphology J:183486
abnormal PP cell differentiation J:183486
decreased embryo size J:183486
lethality throughout fetal growth and development, incomplete penetrance J:183486
small pancreas J:183486
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory