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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tgfbr3
transforming growth factor, beta receptor III
MGI:104637
42 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Tgfbr3em1(IMPC)Mbp/Tgfbr3+
C57BL/6N-Tgfbr3em1(IMPC)Mbp/MbpMmucd
abnormal blood vessel morphology J:211773
abnormal kidney morphology J:211773
abnormal placenta morphology J:211773
abnormal placenta vasculature J:211773
enlarged kidney J:211773
microphthalmia J:211773
Tgfbr3em1(IMPC)Mbp/Tgfbr3em1(IMPC)Mbp
C57BL/6N-Tgfbr3em1(IMPC)Mbp/MbpMmucd
abnormal blood vessel morphology J:211773
abnormal placenta morphology J:211773
abnormal placenta vasculature J:211773
edema J:211773
embryonic growth retardation J:211773
hemorrhage J:211773
pale liver J:211773
preweaning lethality, complete penetrance J:211773
Tgfbr3tm1.1Jba/Tgfbr3tm1.1Jba
involves: 129S6/SvEvTac
abnormal palatal shelf bone ossification J:218259
abnormal palatal shelf fusion at midline J:218259
abnormal palate development J:218259
abnormal vasculogenesis J:218259
decreased palatal shelf size J:218259
decreased tongue size J:218259
failure of palatal shelf elevation J:218259
lethality throughout fetal growth and development, complete penetrance J:218259
Tgfbr3tm1.1Jba/Tgfbr3tm1.1Jba
involves: 129S6/SvEvTac * C57BL/6
abnormal epicardium morphology J:141344
abnormal truncus arteriosus septation J:141344
abnormal vasculogenesis J:141344
lethality throughout fetal growth and development, complete penetrance J:141344
thin myocardium J:141344
transposition of great arteries J:141344
Tgfbr3tm1Stv/Tgfbr3tm1Stv
involves: 129/Sv * C57BL/6
abnormal axial skeleton morphology J:83727
abnormal definitive hematopoiesis J:83727
abnormal femur morphology J:83727
abnormal fertility/fecundity J:83727
abnormal fetal cardiomyocyte proliferation J:83727
abnormal interventricular septum muscular part morphology J:83727
abnormal liver development J:83727
abnormal skeleton development J:83727
abnormal spleen morphology J:83727
abnormal sternum morphology J:83727
abnormal trochanter morphology J:83727
absent deltoid tuberosity J:83727
decreased myocardial fiber number J:83727
decreased spleen white pulp amount J:83727
lethality throughout fetal growth and development, incomplete penetrance J:83727
muscular ventricular septal defect J:83727
rib fusion J:83727
trabecula carnea hypoplasia J:83727
ventricle myocardium hypoplasia J:83727

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory