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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atoh1
atonal bHLH transcription factor 1
MGI:104654
15 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atoh1tm2Hzo/Atoh1+
Tcf4tm1Zhu/Tcf4+
involves: 129P2/OlaHsd 		abnormal brain development J:125313
neonatal lethality J:125313
Atoh1tm2Hzo/Atoh1+
Gfi1tm1Sho/Gfi1tm1Sho
involves: 129S1/Sv * C57BL/6J 		abnormal cochlear hair cell morphology J:80025
abnormal vestibular hair cell morphology J:80025
abnormal vestibular hair cell stereociliary bundle morphology J:80025
cochlear hair cell degeneration J:80025
Atoh1tm3Hzo/Atoh1+
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sortm1(Smo/EYFP)Amc
involves: 129 * 129S7/SvEvBrd * 129X1/SvJ 		abnormal cerebellum external granule cell layer morphology J:155047
abnormal cerebellum morphology J:155047
abnormal neuronal precursor proliferation J:155047
irregular external granule cell layer thickness J:155047
Atoh1tm3Hzo/Atoh1tm1Hzo
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sortm1(Smo/EYFP)Amc
involves: 129 * 129S7/SvEvBrd * 129X1/SvJ 		abnormal neuronal precursor proliferation J:155047
cerebellum atrophy J:155047
thin external granule cell layer J:155047
Atoh1tm4.1Hzo/Atoh1+
Piezo2tm2.2Apat/Piezo2tm2.2Apat
Tg(KRT14-cre)1Amc/0
involves: 129S7/SvEvBrd * C57BL/6 * CBA 		abnormal mechanical nociception J:211312
abnormal nervous system electrophysiology J:211312
Atoh1tm6.1Hzo/Atoh1tm6.1Hzo
involves: 129S7/SvEvBrd * C57BL/6 * SJL 		no abnormal phenotype detected J:155047
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory