Soat1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Soat1
sterol O-acyltransferase 1
MGI:104665

19 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Soat1^ald/Soat1^ald AKR	abnormal hair growth	J:15247
	abnormal hair medulla	J:15247
	abnormal hair shaft morphology	J:15247
Soat1^ald/Soat1^ald AKR/O	abnormal adrenal cortex morphology	J:5089, J:12157
	abnormal adrenocortical cell morphology	J:12157
	increased leukemia incidence	J:12157
	thymus hyperplasia	J:12157
Soat1^m1Anu/Soat1^m1Anu C57BL/6NCrlAnu-Soat1^m1Anu	normal immune system phenotype	J:104190
Soat1^tm1Far/Soat1^tm1Far involves: 129S4/SvJae * C57BL/6	abnormal adrenal gland morphology	J:37049
	abnormal cholesterol homeostasis	J:37049
	abnormal lipid level	J:37049
	abnormal liver morphology	J:37049
	abnormal macrophage morphology	J:37049
	increased circulating cholesterol level	J:37049
	increased circulating HDL cholesterol level	J:37049
Soat1^tm1Ishi/Soat1^tm1Ishi involves: 129S7/SvEvBrd * C57BL/6	abnormal lipid homeostasis	J:63468
	dry eyes	J:63468
	Meibomian gland atrophy	J:63468
	narrow eye opening	J:63468

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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