Soat1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Soat1
sterol O-acyltransferase 1
MGI:104665

27 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Unc/Apoe^tm1Unc Soat1^tm1Far/Soat1^tm1Far involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J	abnormal brain morphology	J:61147
	abnormal cholesterol homeostasis	J:61147
	abnormal cholesterol level	J:61147
	abnormal coat appearance	J:61147
	abnormal dermal layer morphology	J:61147
	abnormal skin condition	J:61147
	abnormal skin morphology	J:61147
	atherosclerotic lesions	J:61147
	decreased circulating cholesterol level	J:61147
	decreased circulating VLDL cholesterol level	J:61147
	hyperkeratosis	J:61147
	skin fibrosis	J:61147
	skin inflammation	J:61147
	skin lesions	J:61147
	sparse hair	J:61147
	thick dermal layer	J:61147
	xanthoma	J:61147
Ldlr^tm1Her/Ldlr^tm1Her Soat1^tm1Far/Soat1^tm1Far involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J	abnormal brain morphology	J:61147
	abnormal cerebellum morphology	J:61147
	abnormal dermal layer morphology	J:61147
	atherosclerotic lesions	J:61147
	decreased circulating cholesterol level	J:61147
	skin edema	J:61147
	skin inflammation	J:61147
	skin lesions	J:61147
	thick skin	J:61147
	xanthoma	J:61147
Soat1^tm1Ishi/Soat1^tm1Ishi Apoe^tm1Unc/Apoe^tm1Unc involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6	abnormal dermal layer morphology	J:63468
	abnormal lipid homeostasis	J:63468
	abnormal skin condition	J:63468
	alopecia	J:63468
	decreased hair follicle number	J:63468
	dry eyes	J:63468
	increased circulating cholesterol level	J:63468
	Meibomian gland atrophy	J:63468
	mixed cellular infiltration to dermis	J:63468
	skin lesions	J:63468
	thick dermal layer	J:63468
	thick skin	J:63468
	xanthoma	J:63468
Soat1^tm1Ishi/Soat1^tm1Ishi Ldlr^tm1Her/Ldlr^tm1Her involves: 129S7/SvEvBrd * C57BL/6	abnormal lipid homeostasis	J:63468
	dry eyes	J:63468
	increased circulating cholesterol level	J:63468
	Meibomian gland atrophy	J:63468
	xanthoma	J:63468

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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