Fkbp5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fkbp5
FK506 binding protein 5
MGI:104670

12 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fkbp5^{Gt(RRC236)Byg}/Fkbp5^{Gt(RRC236)Byg} involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:120960
Fkbp5^{tm1b(KOMP)Wtsi}/Fkbp5⁺ C57BL/6N-Fkbp5^{tm1b(KOMP)Wtsi}/MbpMmucd	increased kidney weight	J:211773
	increased lean body mass	J:211773
Fkbp5^{tm1b(KOMP)Wtsi}/Fkbp5^{tm1b(KOMP)Wtsi} C57BL/6N-Fkbp5^{tm1b(KOMP)Wtsi}/MbpMmucd	cornea opacity	J:211773
	increased basophil cell number	J:211773
	increased kidney weight	J:211773
	increased neutrophil cell number	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Fkbp5^tm1Dvds/Fkbp5^tm1Dvds involves: 129X1/SvJ	normal reproductive system phenotype	J:101405
Fkbp5^tm1Dvds/Fkbp5^tm1Dvds involves: 129X1/SvJ * C57BL/6 * Swiss Webster	normal behavior/neurological phenotype	J:177683
	decreased circulating corticosterone level	J:177683
	decreased depression-related behavior	J:177683
	increased anxiety-related response	J:177683

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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