About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Twist2
twist basic helix-loop-helix transcription factor 2
MGI:104685
49 phenotypes from 3 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Twist2tm1(cre)Dor/Twist2+
involves: 129X1/SvJ 		no abnormal phenotype detected J:90391
Twist2tm1(cre)Dor/Twist2tm1(cre)Dor
involves: 129/Sv * 129X1/SvJ 		abnormal brown fat cell morphology J:81485
abnormal hair follicle morphology J:81485
abnormal hepatocyte morphology J:81485
abnormal interleukin level J:81485
abnormal interscapular fat pad morphology J:81485
abnormal osteoblast differentiation J:90056
abnormal skeletal muscle morphology J:81485
abnormal spleen morphology J:81485
abnormal spleen white pulp morphology J:81485
abnormal thymus cortex morphology J:81485
abnormal thymus medulla morphology J:81485
abnormal thymus morphology J:81485
abnormal tumor necrosis factor level J:81485
absent subcutaneous adipose tissue J:81485
cachexia J:81485
decreased hair follicle number J:81485
decreased liver glycogen level J:81485
decreased skeletal muscle glycogen level J:81485
decreased total body fat amount J:81485
dystonia J:81485
epidermal atrophy J:81485
hyperkeratosis J:81485
hypoglycemia J:81485
postnatal lethality, incomplete penetrance J:81485
sparse hair J:81485
thin dermal layer J:81485
thin skin J:81485
thymus atrophy J:81485
Twist2tm1(cre)Dor/Twist2tm1(cre)Dor
involves: 129X1/SvJ * C57BL/6 		abnormal craniofacial morphology J:169191
abnormal dermal layer morphology J:169191
abnormal eye morphology J:169191
abnormal hair growth J:169191
abnormal head morphology J:169191
abnormal skin adnexa morphology J:169191
absent Meibomian glands J:169191
alopecia J:169191
decreased subcutaneous adipose tissue amount J:169191
loss of eyelid cilia J:169191
lowered ear position J:169191
Meibomian gland hypoplasia J:169191
narrow snout J:169191
skin lesions J:169191
sparse hair J:169191
thin skin J:169191
Twist2tm1.1(cre)Dor/Twist2+
involves: 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:81485
Twist2tm1.1(KOMP)Vlcg/Twist2+
C57BL/6N-Twist2tm1.1(KOMP)Vlcg/Ucd 		abnormal lung morphology J:211773
abnormal testis morphology J:211773
enlarged lung J:211773
increased lung weight J:211773
small testis J:211773
Twist2tm1.1(KOMP)Vlcg/Twist2tm1.1(KOMP)Vlcg
C57BL/6N-Twist2tm1.1(KOMP)Vlcg/Ucd 		preweaning lethality, incomplete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory