Ndst1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ndst1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
MGI:104719

31 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ndst1^tm1.1Grob/Ndst1⁺ Shh^tm1Chg/Shh⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal eye development	J:100425
	abnormal maxillary prominence morphology	J:100425
	absent olfactory epithelium	J:100425
	absent tongue	J:100425
	aphakia	J:100425
	frontonasal prominence hypoplasia	J:100425
	mandible hypoplasia	J:100425
	microphthalmia	J:100425
	small snout	J:100425
Ndst1^tm1.1Grob/Ndst1^tm1.1Grob Ndst3^tm1.1Grob/Ndst3^tm1.1Grob involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	abnormal brain morphology	J:138557
	abnormal eye morphology	J:138557
	abnormal face development	J:138557
	abnormal forebrain morphology	J:138557
	abnormal maxillary prominence morphology	J:138557
	abnormal viscerocranium morphology	J:138557
	absent mandible	J:138557
	anophthalmia	J:138557
	decreased fibroblast cell migration	J:138557
	facial cleft	J:138557
	frontonasal prominence hypoplasia	J:138557
	holoprosencephaly	J:138557
	increased hindbrain apoptosis	J:138557
	lethality throughout fetal growth and development, incomplete penetrance	J:138557
	maxillary shelf hypoplasia	J:138557
	microphthalmia	J:138557
	neonatal lethality, complete penetrance	J:138557
Ndst1^tm1.1Grob/Ndst1^tm1.1Grob Shh^tm1Chg/Shh⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal forebrain morphology	J:100425
	abnormal maxillary prominence morphology	J:100425
	abnormal midbrain morphology	J:100425
	frontonasal prominence hypoplasia	J:100425
	prenatal lethality	J:100425
Ndst1^tm1Grob/Ndst1^tm1Grob Ndst2^tm1Lkj/Ndst2^tm1Lkj H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J	abnormal lacrimal gland development	J:185652
	absent lacrimal glands	J:185652
Ndst1^tm1Grob/Ndst1^tm1Grob Ndst2^tm1Lkj/Ndst2^tm1Lkj Tg(Pax6-cre,GFP)1Pgr/0 involves: 129S1/Sv * 129X1/SvJ * FVB/N	absent lacrimal glands	J:130571
Ndst1^tm1Je/Ndst1^tm1Je Ndst2^tm1Lkj/Ndst2^tm1Lkj Tg(Tek-cre)1Ywa/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	prenatal lethality, complete penetrance	J:100456
Ndst1^tm1Je/Ndst1^tm1Je Robo4^tm1Kzh/Robo4⁺ Tg(Tek-cre)1Ywa/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal diaphragm morphology	J:208012
	abnormal vascular development	J:208012
	diaphragmatic hernia	J:208012
Ndst1^tm1Je/Ndst1^tm1Je Robo4^tm1Kzh/Robo4^tm1Kzh Tg(Tek-cre)1Ywa/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal diaphragm morphology	J:208012
	abnormal vascular development	J:208012
	diaphragmatic hernia	J:208012
Ndst1^tm1Je/Ndst1^tm1Je Slit3^tm1.1Dor/Slit3⁺ Tg(Tek-cre)1Ywa/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	diaphragmatic hernia	J:208012
Ndst1^tm1Je/Ndst1^tm1Je Slit3^tm1.1Dor/Slit3^tm1.1Dor Tg(Tek-cre)1Ywa/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	diaphragmatic hernia	J:208012

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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