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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fgf9
fibroblast growth factor 9
MGI:104723
151 phenotypes from 10 alleles in 12 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fgf9Aca12/Fgf9+
involves: C57BL/6J 		abnormal vision J:176356
increased eye anterior chamber depth J:176356
small lens J:176356
normal vision/eye phenotype J:176356
Fgf9Aca12/Fgf9Aca12
involves: C57BL/6J 		abnormal lens development J:176356
abnormal vision J:176356
cataract J:176356
increased eye anterior chamber depth J:176356
normal mortality/aging J:176356
normal reproductive system phenotype J:176356
normal skeleton phenotype J:176356
small lens J:176356
normal vision/eye phenotype J:176356
Fgf9Eks/Fgf9+
involves: C57BL/6J * DBA/2J 		fused joints J:77537
kinked tail J:77537
lethality at weaning, incomplete penetrance J:77537
postnatal growth retardation J:77537
synostosis J:146802
Fgf9Eks/Fgf9Eks
involves: C57BL/6J * DBA/2J 		abnormal humerus morphology J:77537
abnormal joint morphology J:77537
abnormal long bone morphology J:77537
abnormal lung morphology J:77537
abnormal radius morphology J:77537
abnormal sternum morphology J:77537
abnormal temporal bone morphology J:77537
abnormal vertebral arch morphology J:77537
abnormal voluntary movement J:77537
cleft secondary palate J:77537
cyanosis J:77537
enlarged Meckel's cartilage J:77537
exophthalmos J:77537
fusion of vertebral arches J:77537
high forehead J:77537
hypopnea J:77537
increased cochlea size J:77537
increased diameter of femur J:77537
increased diameter of fibula J:77537
increased diameter of humerus J:77537
increased diameter of radius J:77537
increased diameter of tibia J:77537
increased diameter of ulna J:77537
increased tympanic ring size J:77537
midface hypoplasia J:77537
neonatal lethality, complete penetrance J:77537
ocular hypertelorism J:77537
premature coronal suture closure J:77537, J:146802
premature sagittal suture closure J:77537
short femur J:77537
short fibula J:77537
short humerus J:77537
short limbs J:77537
short nasal bone J:77537
short premaxilla J:77537
short radius J:77537
short sternum J:77537
short tail J:77537
short tibia J:77537
short ulna J:77537
small lung J:77537
synostosis J:77537, J:146802
wide ribs J:77537
Fgf9Eks/Fgf9tm1Dor
involves: 129S6/SvEvTac * C57BL/6J * DBA/2J 		synostosis J:146802
Fgf9tm1.1Fwan/Fgf9tm1.1Fwan
involves: 129S4/SvJaeSor * C57BL/6 		no abnormal phenotype detected J:106766
Fgf9tm1.2Fwan/Fgf9tm1.2Fwan
involves: 129S4/SvJaeSor * C57BL/6 		pallor J:106766
perinatal lethality, complete penetrance J:106766
pulmonary hypoplasia J:106766
respiratory distress J:106766
small lung J:106766
Fgf9tm1.2Zqch/Fgf9+
involves: 129S6/SvEvTac * C57BL/6J * FVB 		abnormal secondary palate development J:306390
delayed palatal shelf elevation J:306390
small mandible J:306390
Fgf9tm1.2Zqch/Fgf9tm1.2Zqch
involves: 129S6/SvEvTac * C57BL/6J * FVB 		abnormal cartilage physiology J:306390
abnormal occipital bone morphology J:306390
abnormal palatal mesenchymal cell proliferation J:306390
abnormal palate bone morphology J:306390
abnormal premaxilla morphology J:306390
abnormal secondary palate development J:306390
abnormal secondary palate morphology J:306390
abnormal tongue position J:306390
cleft secondary palate J:306390
decreased hyaluronic acid level J:306390
decreased mouth size J:306390
decreased palatal shelf size J:306390
delayed palatal shelf elevation J:306390
increased tongue size J:306390
narrow head J:306390
narrow palate J:306390
neonatal lethality, complete penetrance J:306390
premature bone ossification J:306390
short mandible J:306390
small mandible J:306390
Fgf9tm1b(KOMP)Wtsi/Fgf9+
C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H 		abnormal retina vasculature morphology J:211773
cataract J:211773
decreased spleen weight J:211773
enlarged heart J:211773
hyperactivity J:211773
Fgf9tm1b(KOMP)Wtsi/Fgf9+
C57BL/6N-Fgf9tm1b(KOMP)Wtsi/J 		increased heart weight J:211773
Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H 		preweaning lethality, complete penetrance J:211773
Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
C57BL/6N-Fgf9tm1b(KOMP)Wtsi/J 		abnormal body wall morphology J:211773
abnormal embryo size J:211773
cleft palate J:211773
preweaning lethality, complete penetrance J:211773
Fgf9tm1Dor/Fgf9+
involves: 129S6/SvEvTac 		synostosis J:146802
Fgf9tm1Dor/Fgf9tm1Dor
involves: 129S6/SvEvTac 		abnormal lung-associated mesenchyme development J:107406
Fgf9tm1Dor/Fgf9tm1Dor
involves: 129S6/SvEvTac * C57BL/6 		abnormal branching involved in lung morphogenesis J:69852
abnormal cecum morphology J:104353
abnormal digestive system physiology J:139005
abnormal Leydig cell differentiation J:68379
abnormal mesenchymal cell proliferation involved in lung development J:69852
abnormal primary sex determination J:68379
abnormal Sertoli cell development J:68379
abnormal small intestine crypts of Lieberkuhn morphology J:139005
abnormal small intestine morphology J:139005
abnormal testis cord formation J:68379
abnormal testis morphology J:68379
cleft palate J:69852
cyanosis J:69852
decreased fetal weight J:69852
decreased lung weight J:69852
decreased number of peritubular myoid cells J:68379
dilated heart atrium J:69852
dilated heart ventricle J:69852
disorganized testis cords J:68379
normal endocrine/exocrine gland phenotype J:68379
epididymis hypoplasia J:68379
hypoxia J:69852
neonatal lethality, complete penetrance J:69852
ovotestis J:68379
perinatal lethality, complete penetrance J:68379
primary sex reversal J:68379
pulmonary hypoplasia J:69852
respiratory failure J:69852
testis hypoplasia J:68379
Fgf9tm1Dor/Fgf9tm1Dor
involves: C57BL/6J 		abnormal fetal cardiomyocyte proliferation J:95803
abnormal heart development J:95803
dilated heart left ventricle J:95803
dilated heart right ventricle J:95803
heart hypoplasia J:95803
increased heart atrium size J:95803
Fgf9tm1Fwan/Fgf9tm1Fwan
involves: 129S4/SvJaeSor * C57BL/6 		postnatal lethality, incomplete penetrance J:106766
Fgf9tm1Zgwg/Fgf9+
involves: 129S1/Sv 		abnormal coccyx morphology J:241783
abnormal incisor morphology J:241783
abnormal intervertebral disk morphology J:241783
abnormal joint morphology J:241783
abnormal tooth development J:241783
abnormal voluntary movement J:241783
curly tail J:241783
fused joints J:241783
increased bone ossification J:241783
misaligned incisors J:241783
synostosis J:241783
vertebral fusion J:241783
Fgf9tm1Zgwg/Fgf9tm1Zgwg
involves: 129S1/Sv 		abnormal cartilage development J:241783
abnormal joint morphology J:241783
abnormal knee joint morphology J:241783
abnormal limb development J:241783
abnormal suckling behavior J:241783
abnormal testis morphology J:241783
abnormal voluntary movement J:241783
calcified joint J:241783
caudal vertebral fusion J:241783
curly tail J:241783
delayed bone ossification J:241783
fused joints J:241783
increased bone ossification J:241783
increased chondrocyte number J:241783
postnatal lethality J:241783
normal renal/urinary system phenotype J:241783
normal respiratory system phenotype J:241783
synostosis J:241783
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-Fgf9,-EGFP)#Dor/0
involves: FVB 		abnormal branching involved in lung morphogenesis J:224791
abnormal lung epithelium morphology J:224791
abnormal lung-associated mesenchyme development J:224791
ascites J:204282
increased blastoma incidence J:224791
increased lung adenocarcinoma incidence J:204282
increased lung adenoma incidence J:204282
increased lung tumor incidence J:204282
increased malignant tumor incidence J:204282
increased mesenchymal cell proliferation involved in lung development J:224791
premature death J:204282
respiratory failure J:204282
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-Fgf9,-EGFP)#Dor/0
Not Specified 		abnormal branching involved in lung morphogenesis J:107406
abnormal lung development J:107406
abnormal lung epithelium morphology J:107406
abnormal lung vasculature morphology J:107406
abnormal lung-associated mesenchyme development J:107406
enlarged lung J:107406
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory