About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fdxr
ferredoxin reductase
MGI:104724
33 phenotypes from 2 alleles in 2 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Fdxrem1(IMPC)Bay/Fdxrem1(IMPC)Bay
C57BL/6N-Fdxrem1(IMPC)Bay/BayMmucd 		preweaning lethality, complete penetrance J:211773
Fdxrtm1Xch/Fdxr+
B6.Cg-Fdxrtm1Xch 		abnormal iron homeostasis J:244082
abnormal iron level J:244082
abnormal mitochondrial morphology J:244082
abnormal protein level J:244082
chronic liver inflammation J:244082
decreased cell death J:244082
hepatic steatosis J:244082
increased alpha-fetoprotein level J:244082
increased B cell derived lymphoma incidence J:244082
increased fibroblast proliferation J:244082
increased hemangioma incidence J:244082
increased hemangiosarcoma incidence J:244082
increased hepatocellular carcinoma incidence J:244082
increased liver iron level J:244082
increased liver tumor incidence J:244082
increased lung carcinoma incidence J:244082
increased lymphoma incidence J:244082
increased myeloid sarcoma incidence J:244082
increased plasmacytoma incidence J:244082
increased sarcoma incidence J:244082
increased T cell derived lymphoma incidence J:244082
increased tumor incidence J:244082
premature death J:244082
Fdxrtm1Xch/Fdxrtm1Xch
B6.Cg-Fdxrtm1Xch 		abnormal embryo development J:244082
abnormal embryonic epiblast morphology J:244082
abnormal embryonic tissue morphology J:244082
abnormal extraembryonic ectoderm morphology J:244082
abnormal extraembryonic endoderm morphology J:244082
abnormal extraembryonic tissue morphology J:244082
abnormal iron level J:244082
abnormal mesoderm morphology J:244082
abnormal visceral endoderm morphology J:244082
embryonic lethality between somite formation and embryo turning, complete penetrance J:244082
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory