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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cplx1
complexin 1
MGI:104727
12 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cplx1tm2Bros/Cplx1tm2Bros
Cplx2tm1Bros/Cplx2tm1Bros
Not Specified 		abnormal CNS synaptic transmission J:86365
abnormal inhibitory postsynaptic currents J:136393
abnormal neuron physiology J:136393
abnormal neurotransmitter secretion J:136393
abnormal pre-Botzinger complex physiology J:136393
decreased excitatory postsynaptic current amplitude J:136393
decreased miniature excitatory postsynaptic current amplitude J:136393
decreased miniature excitatory postsynaptic current frequency J:136393
impaired synaptic plasticity J:136393
neonatal lethality, complete penetrance J:86365, J:136393
Cplx1tm2Bros/Cplx1tm2Bros
Cplx2tm1Bros/Cplx2tm1Bros
Cplx3tm1Bros/Cplx3tm1Bros
Not Specified 		abnormal inhibitory postsynaptic currents J:136393
abnormal miniature excitatory postsynaptic currents J:136393
abnormal neuron physiology J:136393
abnormal neurotransmitter secretion J:136393
abnormal pre-Botzinger complex physiology J:136393
decreased excitatory postsynaptic current amplitude J:136393
decreased excitatory postsynaptic current frequency J:136393
impaired synaptic plasticity J:136393
neonatal lethality, complete penetrance J:136393
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory