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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cdkn2b
cyclin dependent kinase inhibitor 2B
MGI:104737
21 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Cdkn2btm1Bbd/Cdkn2btm1Bbd
involves: 129S1/Sv * C57BL/6
abnormal cell physiology J:63299
abnormal lymph node germinal center morphology J:63299
abnormal lymph node secondary follicle morphology J:63299
abnormal lymphocyte morphology J:63299
abnormal spleen marginal zone morphology J:63299
abnormal spleen morphology J:63299
extramedullary hematopoiesis J:63299
increased adenocarcinoma incidence J:63299
increased fibroblast proliferation J:63299
increased mature B cell number J:63299
increased sarcoma incidence J:63299
increased tumor incidence J:63299
lymph node hyperplasia J:63299
lymphoid hyperplasia J:63299
premature death J:63299
spleen hyperplasia J:63299
Cdkn2btm1Wff/Cdkn2btm1Wff
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
abnormal common myeloid progenitor cell morphology J:163498
abnormal megakaryocyte progenitor cell morphology J:163498
decreased erythroid progenitor cell number J:163498
increased monocyte cell number J:163498
myeloid hyperplasia J:163498

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory